Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.69 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29440670 | 1.00 | OPRD1 (0.69) | OPRD1OPRM1OPRK1 | |
| Frakefamide SCHEMBL29388146 | 0.95 | OPRD1 (0.63) | OPRD1OPRM1OPRK1 | |
| SCHEMBL30661444 | 0.92 | OPRD1 (0.70) | OPRD1OPRM1OPRK1 | |
| SCHEMBL31140206 | 0.92 | OPRD1 (0.80) | OPRD1OPRM1OPRK1 | |
| SCHEMBL27755089 | 0.91 | ACE (0.60) | — | |
| SCHEMBL29437738 | 0.91 | ACE (0.60) | — | |
| SCHEMBL30786035 | 0.90 | OPRD1 (0.69) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29789555 | 0.90 | OPRD1 (0.69) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29365670 | 0.89 | NPY4R (0.62) | OPRD1OPRM1OPRK1 | |
| SCHEMBL7900841 | 0.88 | OPRD1 (0.74) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624002-B2 | Dimers for use in synthesis of peptidomimetics | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2026-05-12 | — | — | US | disclosed |
| US-12600699-B2 | Thiosemicarbazates and uses thereof | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2026-04-14 | — | — | US | disclosed |
| US-12595233-B2 | Thiosemicarbazates and uses thereof | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2026-04-07 | — | — | US | disclosed |
| US-20260070894-A1 | COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2026-03-12 | — | — | US | disclosed |
| US-12351573-B2 | Compounds for use in synthesis of peptidomimetics | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2025-07-08 | — | — | US | disclosed |
| US-20230159450-A1 | DIMERS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH | 2023-05-25 | — | — | US | disclosed |
| US-20230111252-A1 | THIOSEMICARBAZATES AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2023-04-13 | — | — | US | disclosed |
| EP-4146629-A1 | DIMERS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | The Feinstein Institutes for Medical Research (US) | 2023-03-15 | — | — | EP | disclosed |
| CN-115515937-A | Dimers for the synthesis of peptidomimetics | 范因斯坦医学研究院 | 2022-12-23 | — | — | CN | disclosed |
| US-20220372022-A1 | COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2022-11-24 | — | — | US | disclosed |
| US-20150051371-A1 | CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF | NEKTAR THERAPEUTICS (US) | 2015-02-19 | — | — | US | disclosed |
| US-20130281657-A1 | MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-10-24 | — | — | US | disclosed |
| US-20130281657-A1 | MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-10-24 | — | — | US | disclosed |
| EP-2627662-A1 | METHODS FOR PREPARING MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | Bristol-Myers Squibb Company (US) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012051405-A1 | METHODS FOR PREPARING MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-04-19 | — | — | WO | disclosed |
| US-20110288011-A1 | PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF | ANGIOCHEM INC. (CA) | 2011-11-24 | — | — | US | disclosed |
| US-20110171312-A1 | MODIFIED THERAPEUTIC PEPTIDES, METHODS OF THEIR PREPARATION AND USE | NEKTAR THERAPEUTICS (US) | 2011-07-14 | — | — | US | disclosed |
| EP-2341942-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | Nektar Therapeutics (US) | 2011-07-13 | — | — | EP | disclosed |
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-07 | — | — | US | disclosed |
| WO-2010033207-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS (US) | 2010-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12351573-B2 | Compounds for use in synthesis of peptidomimetics | DNPEP, NPEPPS, PAM | OPRD1 2574/4885OPRM1 1752/4885OPRK1 2628/4885 |
| US-12624002-B2 | Dimers for use in synthesis of peptidomimetics | GLUL, ARGLU1, ASNS | OPRD1 905/4885OPRM1 1215/4885OPRK1 2463/4885 |
| US-20150051371-A1 | CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF | STT3B, STT3A, DDOST | OPRD1 3859/4885OPRM1 3352/4885OPRK1 3229/4885 |
| US-20260070894-A1 | COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | NPR1, NGLY1, DDAH1 | OPRD1 1029/4885OPRM1 453/4885OPRK1 1473/4885 |
| US-12595233-B2 | Thiosemicarbazates and uses thereof | TST, THRB, HSPB1 | OPRD1 2834/4885OPRM1 1506/4885OPRK1 3659/4885 |
| US-20230111252-A1 | THIOSEMICARBAZATES AND USES THEREOF | TST, ABAT, AADAC | OPRD1 4147/4885OPRM1 3052/4885OPRK1 4194/4885 |
| US-20220372022-A1 | COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | DNPEP, NPEPPS, PAM | OPRD1 2574/4885OPRM1 1752/4885OPRK1 2628/4885 |
| US-20110166063-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | OPRD1 3100/4885OPRM1 2317/4885OPRK1 2737/4885 |
| US-20130281657-A1 | MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | PTMS, VIP, MTPN | OPRD1 4530/4885OPRM1 4478/4885OPRK1 4371/4885 |
| US-20230159450-A1 | DIMERS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | DNPEP, DAP3, ANPEP | OPRD1 4010/4885OPRM1 2471/4885OPRK1 3891/4885 |
| US-20110171312-A1 | MODIFIED THERAPEUTIC PEPTIDES, METHODS OF THEIR PREPARATION AND USE | DNPEP, VIP, PTMS | OPRD1 2871/4885OPRM1 1535/4885OPRK1 2169/4885 |
| US-12600699-B2 | Thiosemicarbazates and uses thereof | MET, THRB, ABAT | OPRD1 2236/4885OPRM1 780/4885OPRK1 2051/4885 |
| US-20110288011-A1 | PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF | VIP, SLC1A5, SLC47A1 | OPRD1 4036/4885OPRM1 3822/4885OPRK1 3911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.