SCHEMBL7900855

SCHEMBL7900855

CC(=O)CCC(=O)CCCCC(C)C

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
KDM4C Q9H3R0 2/20 0.41
KDM4A O75164 1/20 0.41
PHF8 Q9UPP1 1/20 0.41
KDM2A Q9Y2K7 1/20 0.41
KDM1A O60341 1/20 0.40
CA1 P00915 2/20 0.38
LMNA P02545 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
SLC15A2 Q16348 1/20 0.37
PAOX Q6QHF9 1/20 0.37
BLM P54132 1/20 0.36
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
PTPN1 P18031 2/20 0.34
DEGS1 O15121 1/20 0.33
LTA4H P09960 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4575366 0.89 KDM4C (0.47) KDM4CKDM4APHF8KDM2AKDM1A
SCHEMBL290187 0.86 PAOX (0.48) ALDH1A1KDM4CKDM4APHF8KDM2A
SCHEMBL28995086 0.86 KDM4C (0.50) ALDH1A1KDM4CKDM4APHF8KDM2A
SCHEMBL8836038 0.86 KDM4C (0.50) ALDH1A1KDM4CKDM4APHF8KDM2A
SCHEMBL28399899 0.86 KDM4C (0.50) ALDH1A1KDM4CKDM4APHF8KDM2A
SCHEMBL8039193 0.86 KDM4C (0.50) ALDH1A1KDM4CKDM4APHF8KDM2A
SCHEMBL28393903 0.86 KDM4C (0.50) ALDH1A1KDM4CKDM4APHF8KDM2A
SCHEMBL17228593 0.86 KDM4C (0.46) KDM4CKDM4APHF8KDM2AKDM1A
SCHEMBL31300438 0.86 KDM4C (0.50) ALDH1A1KDM4CKDM4APHF8KDM2A
SCHEMBL28847799 0.84 ALDH1A1 (0.50) ALDH1A1PHF8KDM2AKDM1ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0521650-B1 Working fluid composition for use in refrigeration system KAO CORP (JP) 1997-08-13 EP claimed
US-5401433-A Base oils with ketone groups for use with hydrofluorocarbons, air conditioners KAO CORPORATION (JP) 1995-03-28 US claimed
US-6197211-B1 REFRIGERANT COMPRESSION-TYPE CONTAINING THE REFRIGERANT COMPRISING A HALOGEN-FREE HYDROCARBON OF 2-4 CARBONS AND A REFRIGERATION LUBRICANT COMPRISING, AS A MAIN COMPONENT, A POLYKETONE INCOMPATIBLE WITH THE REFRIGERANT MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2001-03-06 US disclosed
EP-0521650-B1 Working fluid composition for use in refrigeration system KAO CORP (JP) 1997-08-13 EP disclosed
US-5401433-A Base oils with ketone groups for use with hydrofluorocarbons, air conditioners KAO CORPORATION (JP) 1995-03-28 US disclosed
US-5300245-A Mixed with hydrofluorocarbons KAO CORPORATION (JP) 1994-04-05 US disclosed
EP-0521650-A1 Working fluid composition for use in refrigeration system Kao Corporation (JP) 1993-01-07 EP disclosed