Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 8/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7891736 | 0.82 | KMT2A (0.44) | KCNA5POLBKMT2AALDH1A1NR1I2 | |
| SCHEMBL15437776 | 0.72 | GABBR2 (0.47) | KMT2AMAPTTSHRLMNA | |
| SCHEMBL2347309 | 0.72 | HPGD (0.57) | KCNA5POLBKMT2AALDH1A1HPGD | |
| SCHEMBL7995142 | 0.71 | ALDH1A1 (0.67) | KCNA5POLBKMT2AALDH1A1HPGD | |
| SCHEMBL12473253 | 0.71 | KCNA5 (0.65) | KCNA5POLBKMT2AALDH1A1HPGD | |
| SCHEMBL5522123 | 0.70 | KCNA5 (0.64) | KCNA5KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL9909376 | 0.70 | KCNA5 (0.64) | KCNA5KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL29740346 | 0.70 | KCNA5 (0.40) | KCNA5POLBKMT2AALDH1A1MAPT | |
| SCHEMBL6230959 | 0.70 | ALDH1A1 (0.47) | KCNA5POLBKMT2AALDH1A1HPGD | |
| SCHEMBL6862384 | 0.69 | KCNA5 (0.51) | KCNA5KMT2AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288268-B1 | REACTION OF OLEFIN WITH ALCOHOL, OXYGEN AND CARBON MONOXIDE IN THE PRESENCE OF CATALYST FOR BISALKOXYCARBONYLATION WITH NOBLE MEYAL AND PHOSPHINE CHALCOGENIDE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2001-09-11 | — | — | US | disclosed |
| US-6184390-B1 | Catalyst for bisalkoxycarbonylation of olefins, and method for production of succinate derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| US-6159891-A | Catalyst for bisalkoxycarbonylation of olefins, and method for production of succinate derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2000-12-12 | — | — | US | disclosed |