Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 4/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3491883 | 0.82 | MCL1 (0.40) | FAAHMCL1 | |
| SCHEMBL3233785 | 0.80 | KMT2A (0.44) | DRD2DRD3NAMPTADORA2AFAAH | |
| SCHEMBL369170 | 0.76 | KDM4E (0.41) | DRD2DRD3FAAHIDH1ALDH1A1 | |
| SCHEMBL5108390 | 0.76 | KDM4E (0.41) | DRD2DRD3FAAHIDH1ALDH1A1 | |
| SCHEMBL3233429 | 0.74 | KDM4E (0.40) | DRD2DRD3ADORA2ACYP2D6FAAH | |
| Hydrochloric Acid SCHEMBL3241637 | 0.74 | KDM4E (0.40) | DRD2DRD3FAAHIDH1DPP8 | |
| SCHEMBL7898049 | 0.73 | CYP2C19 (0.47) | DRD2DRD3ALDH1A1 | |
| SCHEMBL19277248 | 0.72 | GHSR (0.46) | FAAHMCL1 | |
| SCHEMBL537535 | 0.70 | DRD2 (0.46) | DRD2DRD3FAAHIDH1 | |
| SCHEMBL1107078 | 0.70 | DRD2 (0.46) | DRD2DRD3FAAHIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184229-B1 | 6-pyrrolidin-2-ylpyrindine derivatives, their preparation and application in therapy | SANOFI-SYNTHELABO (FR) | 2001-02-06 | — | — | US | disclosed |