Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.36 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10431968 | 0.73 | S100A4 (0.39) | IDO1DNMT1DNMT3LDNMT3AGPR3 | |
| SCHEMBL9557721 | 0.61 | IDO1 (0.56) | IDO1DNMT1DNMT3LDNMT3AGPR3 | |
| SCHEMBL18784868 | 0.59 | GPR3 (0.41) | SLC22A2SLC22A3GPR3HTR2AS100A4 | |
| SCHEMBL2286468 | 0.59 | HTR2A (0.58) | SLC22A2SLC22A3GPR3HTR2ATSHR | |
| SCHEMBL5343918 | 0.59 | GPR3 (0.46) | SLC22A2SLC22A3GPR3HTR2AS100A4 | |
| SCHEMBL31266545 | 0.59 | GPR3 (0.46) | SLC22A2SLC22A3GPR3HTR2AS100A4 | |
| SCHEMBL3885169 | 0.59 | TSHR (0.37) | HTR2ATSHRS100A4CYP2A6 | |
| SCHEMBL10863105 | 0.57 | S100A4 (0.37) | SLC22A2SLC22A3GPR3HTR2ATNKS2 | |
| SCHEMBL29950614 | 0.57 | GPR3 (0.50) | SLC22A2SLC22A3GPR3HTR2A | |
| SCHEMBL524603 | 0.57 | GPR3 (0.50) | SLC22A2SLC22A3GPR3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838476-B1 | Solid precursor of a catalyst system for polymerization of olefins, process for its preparation and catalytic system containing said precursor and process for the polymerization of olefins using said catalyst system | SOLVAY (BE) | 2001-09-26 | — | — | EP | disclosed |
| US-6187882-B1 | POLYMERIZING AN OLEFIN OR MIXTURE THEREOF IN PRESENCE OF A SOLVENT, A SUPPORTED METALLOCENE AND AN ALUMINOXANE AS COCATALYST IN A HYDROCARBON MEDIUM, AT A TEMPERATURE IN THE RANGE OF 50 TO 150 DEGREES C, AT A PRESSURE OF 1 TO 20 BAR | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2001-02-13 | — | — | US | disclosed |