Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25071296 | 0.92 | RAB9A (0.68) | RAB9ANPC1KMT2ASMN1; SMN2USP2 | |
| SCHEMBL17244556 | 0.83 | POLB (0.63) | RAB9ANPC1KMT2ASMN1; SMN2EPHX2 | |
| SCHEMBL7401491 | 0.81 | KMT2A (0.87) | RAB9ANPC1KMT2ASMN1; SMN2EPHX2 | |
| SCHEMBL9312728 | 0.80 | HDAC3 (0.66) | RAB9ANPC1KMT2ASMN1; SMN2HDAC3 | |
| SCHEMBL3332768 | 0.79 | KMT2A (0.63) | RAB9ANPC1KMT2ASMN1; SMN2EPHX2 | |
| SCHEMBL7008242 | 0.79 | IDO1 (0.76) | RAB9ANPC1KMT2ASMN1; SMN2EPHX2 | |
| SCHEMBL1160765 | 0.79 | RAB9A (0.63) | RAB9ANPC1KMT2ASMN1; SMN2EPHX2 | |
| SCHEMBL11208728 | 0.79 | EPHX2 (0.83) | RAB9ANPC1KMT2ASMN1; SMN2EPHX2 | |
| SCHEMBL12545832 | 0.79 | L3MBTL1 (0.65) | RAB9ANPC1KMT2ASMN1; SMN2EPHX2 | |
| SCHEMBL826066 | 0.78 | HDAC3 (0.64) | RAB9ANPC1KMT2ASMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373634-B1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARM CO LTD (JP) | 2015-11-11 | — | — | EP | disclosed |
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |