Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | KCNJ1 | P48048 | 5/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827685 | 0.88 | POLB (0.61) | TSHRLOXL2KCNJ1KCNH2IDO1 | |
| SCHEMBL3292782 | 0.87 | TSHR (0.75) | TSHRLOXL2KCNJ1KCNH2HRH3 | |
| SCHEMBL8094543 | 0.81 | POLB (0.68) | TSHRLOXL2KCNJ1KCNH2HRH3 | |
| SCHEMBL28139668 | 0.80 | ALDH1A1 (0.55) | TSHRLOXL2ALDH1A1CYP19A1 | |
| SCHEMBL16031 | 0.80 | — | — | |
| SCHEMBL13946243 | 0.79 | CYP1A2 (0.67) | TSHRLOXL2KCNJ1KCNH2ALDH1A1 | |
| SCHEMBL18913824 | 0.79 | TSHR (0.69) | TSHRLOXL2KCNJ1KCNH2HRH3 | |
| SCHEMBL30758863 | 0.79 | TSHR (0.69) | TSHRLOXL2KCNJ1KCNH2HRH3 | |
| SCHEMBL4001120 | 0.78 | TSHR (0.58) | TSHRLOXL2KCNJ1KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL1162175 | 0.78 | ALDH1A1 (0.52) | TSHRLOXL2IDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284314-B1 | Porous ceramic thin film and method for production thereof | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY, MINISTRY OF INTERNATIONAL TRADE & INDUSTRY (JP) | 2001-09-04 | — | — | US | disclosed |