Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7901198 | 0.88 | TSHR (0.60) | POLBLOXL2TSHRALDH1A1KMT2A | |
| SCHEMBL8087428 | 0.87 | POLB (0.76) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL44366 | 0.87 | POLB (0.76) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL8094050 | 0.87 | POLB (0.76) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL8094543 | 0.81 | POLB (0.68) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL6979279 | 0.80 | TSHR (0.57) | POLBTSHRALDH1A1KDM4EMEN1 | |
| SCHEMBL28139668 | 0.80 | ALDH1A1 (0.55) | LOXL2CA12CA1CA2CA9 | |
| SCHEMBL16031 | 0.80 | — | — | |
| SCHEMBL267666 | 0.79 | ALDH1A1 (0.70) | POLBLOXL2CA12CA1CA2 | |
| SCHEMBL28372761 | 0.78 | ALDH1A1 (0.52) | LOXL2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989096-B | Thioazole compound and preparation method and application thereof | 赣南师范大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-114989096-A | Thioazole compound and preparation method and application thereof | 赣南师范大学 | 2022-09-02 | — | — | CN | disclosed |
| WO-2004009559-A2 | DIHYDROURACIL COMPOUNDS AS ANTI-ICTOGENIC OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-01-29 | — | — | WO | disclosed |
| EP-0805796-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022966-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1996-08-01 | — | — | WO | disclosed |