Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PRKDC | P78527 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266614 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL30894831 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL12436736 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL9838820 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL3914603 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| Ammonia Solution, Strong SCHEMBL27817247 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL2187742 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL9348477 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL22691535 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPTCYP3A4KDM4EALOX15 | |
| SCHEMBL16285730 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPTCYP3A4KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012036962-A2 | C-TERMINAL AMIDATION OF POLYPEPTIDES | AMYLIN PHARMACEUTICALS, INC. (US) | 2012-03-22 | — | — | WO | disclosed |