Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PRKDC | P78527 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27817247 | 0.98 | ALDH1A1 (0.53) | ALDH1A1CYP3A4KDM4EMAPTALOX15 | |
| SCHEMBL14206877 | 0.91 | ALDH1A1 (0.46) | ALDH1A1CYP3A4KDM4EMAPTALOX15 | |
| SCHEMBL16687486 | 0.88 | TDP1 (0.43) | ALDH1A1CYP3A4KDM4EMAPTALOX15 | |
| SCHEMBL12919856 | 0.86 | TDP1 (0.42) | ALDH1A1CYP3A4KDM4EMAPTALOX15 | |
| SCHEMBL3449786 | 0.86 | ALDH1A1 (0.51) | ALDH1A1CYP3A4KDM4EMAPTALOX15 | |
| SCHEMBL7266614 | 0.86 | ALDH1A1 (0.51) | ALDH1A1CYP3A4KDM4EMAPTALOX15 | |
| SCHEMBL6551658 | 0.86 | CYP3A4 (0.51) | ALDH1A1CYP3A4KDM4EMAPTALOX15 | |
| SCHEMBL18650006 | 0.86 | ALDH1A1 (0.51) | ALDH1A1CYP3A4KDM4EMAPTALOX15 | |
| SCHEMBL13351443 | 0.86 | ALDH1A1 (0.51) | ALDH1A1CYP3A4KDM4EMAPTALOX15 | |
| SCHEMBL9348477 | 0.84 | ALDH1A1 (0.53) | ALDH1A1CYP3A4KDM4EMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322694-A1 | COMPOUND | SUMITOMO CHEMICAL CO., LTD (JP) | 2023-10-12 | — | — | US | disclosed |
| WO-2023280934-A1 | CAP ANALOG FOR THE 5'-END OF EUKARYOTIC MESSENGER RNAS | WESTFÄLISCHE WILHELMS-UNIVERSITÄT (DE) | 2023-01-12 | — | — | WO | disclosed |
| US-11325905-B2 | Imidopiperidine compounds as inhibitors of human polynucleotide kinase phosphatase | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2022-05-10 | — | — | US | disclosed |
| US-20200148675-A1 | IMIDOPIPERIDINE COMPOUNDS AS INHIBITORS OF HUMAN POLYNUCLEOTIDE KINASE PHOSPHATASE | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2020-05-14 | — | — | US | disclosed |
| US-9598713-B2 | Method for constructing functional nucleic acid molecule, and nucleic acid combination to be used in said method | JAPANESE SCIENCE AND TECHNOLOGY AGENCY (JP) | 2017-03-21 | — | — | US | disclosed |
| US-20160015835-A1 | LUCIFERIN DERIVATIVES FROM BICYCLIC REACTANTS AND AMINOTHIOL DERIVATIVES AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-01-21 | — | — | US | disclosed |
| US-9173966-B2 | Luciferin derivatives from bicyclic reactants and aminothiol derivatives and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-11-03 | — | — | US | disclosed |
| US-20150118713-A1 | METHOD FOR CONSTRUCTING FUNCTIONAL NUCLEIC ACID MOLECULE, AND NUCLEIC ACID COMBINATION TO BE USED IN SAID METHOD | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2015-04-30 | — | — | US | disclosed |
| US-20130287699-A1 | Luciferin Derivatives from Bicyclic Reactants and Aminothiol Derivatives and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2013-10-31 | — | — | US | disclosed |
| US-20110178281-A1 | Photocleavable Linker Methods and Compositions | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2011-07-21 | — | — | US | disclosed |
| US-7923562-B2 | Photocleavable linker methods and compositions | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-04-12 | — | — | US | disclosed |
| US-7871982-B2 | Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20100022761-A1 | PHOTOCLEAVABLE LINKER METHODS AND COMPOSITIONS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2010-01-28 | — | — | US | disclosed |
| US-20100022761-A1 | PHOTOCLEAVABLE LINKER METHODS AND COMPOSITIONS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2010-01-28 | — | — | US | disclosed |
| US-20090156512-A1 | potent activity against resistant pneumococci | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
| US-7304168-B2 | Photo-caged fluorescent molecules | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2007-12-04 | — | — | US | disclosed |
| WO-2007065032-A2 | COMPOUNDS AND METHODS FOR INHIBITING VIRAL ENTRY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130287699-A1 | Luciferin Derivatives from Bicyclic Reactants and Aminothiol Derivatives and Methods of Use Thereof | GFPT1, QPCT, GLB1 | ALDH1A1 3234/4885CYP3A4 759/4885KDM4E 4166/4885 |
| US-20160015835-A1 | LUCIFERIN DERIVATIVES FROM BICYCLIC REACTANTS AND AMINOTHIOL DERIVATIVES AND METHODS OF USE THEREOF | GFPT1, QPCT, GLB1 | ALDH1A1 3234/4885CYP3A4 759/4885KDM4E 4166/4885 |
| US-11325905-B2 | Imidopiperidine compounds as inhibitors of human polynucleotide kinase phosphatase | PNKP, PPM1A, PPM1B | ALDH1A1 4037/4885CYP3A4 4663/4885KDM4E 1648/4885 |
| US-20200148675-A1 | IMIDOPIPERIDINE COMPOUNDS AS INHIBITORS OF HUMAN POLYNUCLEOTIDE KINASE PHOSPHATASE | PNKP, PPM1A, PPM1B | ALDH1A1 4037/4885CYP3A4 4663/4885KDM4E 1648/4885 |
| US-20110178281-A1 | Photocleavable Linker Methods and Compositions | NSUN2, RNGTT, METTL16 | ALDH1A1 1111/4885CYP3A4 2188/4885KDM4E 254/4885 |
| US-20100022761-A1 | PHOTOCLEAVABLE LINKER METHODS AND COMPOSITIONS | NSUN2, RNGTT, METTL16 | ALDH1A1 1111/4885CYP3A4 2188/4885KDM4E 254/4885 |
| US-20090156512-A1 | potent activity against resistant pneumococci | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NAT1, NPM1 | ALDH1A1 2976/4885CYP3A4 2690/4885KDM4E 3077/4885 |
| US-20230322694-A1 | COMPOUND | RAD51, NR0B1, XRN2 | ALDH1A1 1331/4885CYP3A4 431/4885KDM4E 2706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.