Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28969460 | 0.95 | NPC1 (0.40) | NPC1RAB9ACNR1CNR2ACSS2 | |
| SCHEMBL768704 | 0.94 | NPC1 (0.42) | NPC1RAB9ACNR1CNR2ACSS2 | |
| SCHEMBL29358618 | 0.94 | NPC1 (0.42) | NPC1RAB9ACNR1CNR2ACSS2 | |
| SCHEMBL6855338 | 0.93 | NPC1 (0.38) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL7523685 | 0.91 | NPC1 (0.41) | NPC1RAB9ACNR1CNR2ACSS2 | |
| SCHEMBL6860552 | 0.90 | NPC1 (0.47) | NPC1RAB9ACNR1CNR2LMNA | |
| SCHEMBL1499910 | 0.89 | NPC1 (0.45) | NPC1RAB9ACNR1CNR2LMNA | |
| SCHEMBL769152 | 0.88 | NPC1 (0.38) | NPC1RAB9ACNR1CNR2ACSS2 | |
| SCHEMBL29377561 | 0.88 | NPC1 (0.38) | NPC1RAB9ACNR1CNR2ACSS2 | |
| SCHEMBL29349567 | 0.88 | NPC1 (0.41) | NPC1RAB9ALMNAPOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268415-B1 | POLYMERS AND STABILIZERS FOR ENHANCED STABILITY | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-31 | — | — | US | claimed |
| CN-1186417-C | Stabilized adhesive compositions containing highly soluble, red-shifted, photostable benzotriazole UV absorbers and laminates made therefrom | CIBA SC HOLDING AG (CH) | 2005-01-26 | — | — | CN | disclosed |
| CN-1349552-A | Stabilized adhesive compositions containing highly soluble, red-shifted, photostable benzotriazole UV absorbers and laminated articles derived therefrom | CIBA SC HOLDING AG (CH) | 2002-05-15 | — | — | CN | disclosed |
| US-6268415-B1 | POLYMERS AND STABILIZERS FOR ENHANCED STABILITY | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-31 | — | — | US | disclosed |
| US-6268415-B1 | POLYMERS AND STABILIZERS FOR ENHANCED STABILITY | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-31 | — | — | US | disclosed |
| US-6187845-B1 | LAMINATION OR MULTILAYER STRUCTURE | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-02-13 | — | — | US | disclosed |