Sugi Predict

Sugi Predict / Compounds / SCHEMBL7523685

SCHEMBL7523685

SCHEMBL7523685

CC(C)(C)c1cc(-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 4/20 0.41
▸ RAB9A P51151 4/20 0.41
▸ ACSS2 Q9NR19 1/20 0.34
▸ LMNA P02545 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ CYP1A2 P05177 2/20 0.33
▸ CYP2C9 P11712 2/20 0.33
▸ CYP2C19 P33261 2/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ KDM4E B2RXH2 4/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.32
▸ MITF O75030 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ KLF5 Q13887 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ MAPT P10636 1/20 0.31
▸ ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7901461 0.91 NPC1 (0.41) NPC1RAB9AACSS2LMNAPOLB
SCHEMBL7519989 0.89 NPC1 (0.45) NPC1RAB9ALMNAPOLBCYP1A2
SCHEMBL29349567 0.88 NPC1 (0.41) NPC1RAB9ALMNAPOLBCYP1A2
SCHEMBL29241 0.88 NPC1 (0.41) NPC1RAB9ALMNAPOLBCYP1A2
Toluene SCHEMBL29114789 0.88 NPC1 (0.46) NPC1RAB9AACSS2LMNAPOLB
SCHEMBL28969460 0.86 NPC1 (0.40) NPC1RAB9AACSS2LMNAPOLB
SCHEMBL768704 0.85 NPC1 (0.42) NPC1RAB9AACSS2LMNAPOLB
SCHEMBL29358618 0.85 NPC1 (0.42) NPC1RAB9AACSS2LMNAPOLB
SCHEMBL11668139 0.84 NPC1 (0.43) NPC1RAB9ALMNAPOLBCYP1A2
Bumetrizole SCHEMBL8250511 0.84 NPC1 (0.54) NPC1RAB9ALMNAPOLBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020169239-A1 2H-benzotriazole UV absorbers substituted with 1,1-diphenylakyl groups and compositions stabilized therewith WOOD MERVIN G (US) 2002-11-14 — — US claimed
US-6392056-B1 FOR THERMOPLASTIC RESINS CIBA SPECIALTY CHEMICAL CORPORATION 2002-05-21 — — US claimed
WO-2002012204-A1 2H-BENZOTRIAZOLE UV ABSORBERS SUBSTITUTED WITH 1,1-DIPHENYLALKYL GROUPS AND COMPOSITIONS STABILIZED THEREWITH CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-02-14 — — WO claimed
US-6489383-B1 SUCH AS 2-(2-HYDROXY-3-(1,1-DI(4-2-(BROMOETHOXY)PHENYL) ETHYL)-5-TERT-BUTYLPHENYL)-2H-BENZOTRIAZOLE FOR USE AS STOVING LACQUER, FINISHING ENAMEL FOR AUTOMOBILES CIBA SPECIALTY CHEMICALS CORPORATION 2002-12-03 — — US disclosed
US-20020169239-A1 2H-benzotriazole UV absorbers substituted with 1,1-diphenylakyl groups and compositions stabilized therewith WOOD MERVIN G (US) 2002-11-14 — — US disclosed
US-6392056-B1 FOR THERMOPLASTIC RESINS CIBA SPECIALTY CHEMICAL CORPORATION 2002-05-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020169239-A1 2H-benzotriazole UV absorbers substituted with 1,1-diphenylakyl groups and compositions stabilized therewith SUV39H1, SUV39H2, PAH NPC1 3986/4885RAB9A 4648/4885ACSS2 3646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.