Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.39 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075801 | 0.81 | ERBB2 (0.35) | PTPRCCA12CA9LMNAPOLB | |
| SCHEMBL49701 | 0.74 | HKDC1 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL28276508 | 0.71 | SETD7 (0.36) | PTPRCTSHRFGFR1FGFR2FGFR4 | |
| SCHEMBL18575642 | 0.69 | ERBB2 (0.39) | PTPRCTSHRCA1CA2CA7 | |
| SCHEMBL9692637 | 0.68 | HSP90AA1 (0.43) | TSHRHSD17B10ALDH1A1KDM4EATM | |
| SCHEMBL9242569 | 0.66 | NPSR1 (0.46) | TSHRFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL10698136 | 0.66 | FGFR1 (0.57) | PTPRCTSHRFGFR1FGFR2FGFR4 | |
| SCHEMBL5145043 | 0.66 | CDC25B (0.43) | LMNAPOLBERBB2ALDH1A1KDM4E | |
| SCHEMBL29006251 | 0.64 | PTPRC (0.50) | PTPRCTSHRSETD7CA1CA2 | |
| SCHEMBL6850637 | 0.64 | SETD7 (0.51) | PTPRCTSHRSETD7CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460996-B1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | OREAL (FR) | 1994-09-14 | — | — | EP | claimed |
| EP-0460996-A1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | L'OREAL (FR) | 1991-12-11 | — | — | EP | claimed |
| EP-0376776-A2 | Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone | L'OREAL (FR) | 1990-07-04 | — | — | EP | claimed |
| US-6179883-B1 | USING 2-IMINO-2,3-DIHYDRO-1H-INDOLE MIXTURE | L'OREAL (FR) | 2001-01-30 | — | — | US | disclosed |
| EP-0826668-B1 | Derivatives of 2-imino-2,3-dihydro-1H-indole and their use in hair dyeing compositions | OREAL (FR) | 1999-06-30 | — | — | EP | disclosed |
| EP-0826668-A1 | Derivatives of 2-imino-2,3-dihydro-1H-indole and their use in hair dyeing compositions | L'OREAL (FR) | 1998-03-04 | — | — | EP | disclosed |
| EP-0603322-B1 | DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES | OREAL (FR) | 1996-12-11 | — | — | EP | disclosed |
| EP-0460996-B1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | OREAL (FR) | 1994-09-14 | — | — | EP | disclosed |
| EP-0603322-A1 | DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES. | OREAL (FR) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993005018-A1 | DYEING COMPOSITION BASED ON HYDROXYINDOLINE DERIVATIVES | L'OREAL (FR) | 1993-03-18 | — | — | WO | disclosed |
| US-5180400-A | METHOD FOR DYEING KERATINOUS FIBRES USING AN AMINOINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE | L'OREAL (FR) | 1993-01-19 | — | — | US | disclosed |
| EP-0376776-B1 | PROCESS FOR DYEING KERATINOUS FIBRES WITH HYDROXYINDOLE ASSOCIATED WITH QUINONE AND 1,4-BENZOQUINONE | L'OREAL (FR) | 1992-09-23 | — | — | EP | disclosed |
| EP-0460996-A1 | Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative | L'OREAL (FR) | 1991-12-11 | — | — | EP | disclosed |
| US-5053053-A | PROCESS FOR DYEING KERATINOUS FIBRES WITH A HYDROXYINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE; AND NOVEL 1,4-BENZOQUINONES | L'OREAL (FR) | 1991-10-01 | — | — | US | disclosed |
| EP-0376776-A2 | Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone | L'OREAL (FR) | 1990-07-04 | — | — | EP | disclosed |