Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 3/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4508150 | 0.85 | HSD17B10 (0.51) | HSD17B10USP2CYP2C9CYP3A4PARP1 | |
| SCHEMBL17244485 | 0.83 | HSD17B10 (0.64) | HSD17B10USP2CYP2C9CYP3A4HPGD | |
| SCHEMBL19049642 | 0.81 | HSD17B10 (0.43) | HSD17B10USP2HPGDPARP1SRD5A1 | |
| SCHEMBL4480763 | 0.81 | SRD5A1 (0.42) | HSD17B10USP2PARP1SRD5A1MAPK1 | |
| SCHEMBL12545693 | 0.78 | HSD17B10 (0.47) | HSD17B10USP2CYP2C9CYP3A4HPGD | |
| SCHEMBL4518789 | 0.78 | HSD17B10 (0.43) | HSD17B10USP2HPGDPARP1SRD5A1 | |
| SCHEMBL17979899 | 0.76 | HSD17B10 (0.59) | HSD17B10USP2CYP2C9CYP3A4HPGD | |
| SCHEMBL22702092 | 0.76 | ALOX5 (0.55) | HSD17B10CYP2C9CYP3A4HPGDPARP1 | |
| SCHEMBL1696787 | 0.76 | USP2 (0.55) | USP2HPGDBRD9AKR1C3KMT2A | |
| SCHEMBL12569511 | 0.76 | DDB1 (0.54) | HSD17B10HPGDBRD9MAPK1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |