Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.31 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.31 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.31 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.31 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904872 | 0.88 | LMNA (0.32) | LMNAMEN1GAAKMT2AGPBAR1 | |
| SCHEMBL12545589 | 0.84 | HTT (0.31) | — | |
| SCHEMBL17244584 | 0.81 | MEN1 (0.45) | LMNAMEN1GAAKMT2A | |
| SCHEMBL12545279 | 0.78 | LMNA (0.33) | LMNAMEN1GAAKMT2A | |
| SCHEMBL6612159 | 0.72 | POLB (0.46) | MEN1GAAKMT2AALDH1A1CYP1A1 | |
| SCHEMBL17409115 | 0.64 | HTR2A (0.39) | LMNAALDH1A1CYP1A1CYP1A2CYP2E1 | |
| SCHEMBL9392519 | 0.64 | PTGS1 (0.48) | LMNAMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL5764953 | 0.64 | POLB (0.44) | GAAKMT2ACYP1A2 | |
| SCHEMBL16301784 | 0.63 | L3MBTL1 (0.39) | LMNAGAAALDH1A1CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL8377423 | 0.62 | PTGS1 (0.43) | LMNAMEN1GAAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373634-B1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARM CO LTD (JP) | 2015-11-11 | — | — | EP | disclosed |
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |