Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | DRD1 | P21728 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 6/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907814 | 1.00 | HSD11B1 (0.41) | HSD11B1DRD2DRD1HTR1APARP1 | |
| SCHEMBL7901664 | 0.90 | DRD2 (0.39) | HSD11B1DRD2DRD1HTR1APARP1 | |
| SCHEMBL15382598 | 0.87 | HSD11B1 (0.39) | HSD11B1DRD2DRD1HTR1APARP1 | |
| SCHEMBL50764 | 0.87 | HSD11B1 (0.39) | HSD11B1DRD2DRD1HTR1APARP1 | |
| SCHEMBL50762 | 0.87 | HSD11B1 (0.39) | HSD11B1DRD2DRD1HTR1APARP1 | |
| SCHEMBL50763 | 0.87 | HSD11B1 (0.39) | HSD11B1DRD2DRD1HTR1APARP1 | |
| SCHEMBL51067 | 0.87 | HSD11B1 (0.39) | HSD11B1DRD2DRD1HTR1APARP1 | |
| SCHEMBL21255627 | 0.87 | HSD11B1 (0.39) | HSD11B1DRD2DRD1HTR1APARP1 | |
| SCHEMBL3322834 | 0.82 | DRD2 (0.40) | DRD2DRD1HTR1A | |
| SCHEMBL51300 | 0.82 | DRD2 (0.56) | DRD2DRD1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097091-A1 | METHODS OF ADMINISTERING (4AR, 1OAR)-I-N-PROPYL-I, 2,3,4A7 S1IO7 IOA-OCTAHYDROBENZO [G] QUINOLINE-6,7-DIOL AND RELATED COMPOUNDS ACROSS THE ORAL MUCOSA, THE NASAL MUCOSA OR THE SKIN AND PHARMACEUTICAL COMPOSITIONS THEREOF | H. LUNDBECK A/S (DK) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010097092-A1 | TREATMENT OF DYSKINESIA RELATED DISORDERS | H. LUNDBECK A/S (DK) | 2010-09-02 | — | — | WO | disclosed |