Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19039347 | 0.84 | USP2 (0.43) | TSHRUSP2CYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL5480087 | 0.81 | GPR84 (0.45) | TSHR | |
| SCHEMBL5269399 | 0.80 | — | — | |
| SCHEMBL4977789 | 0.79 | GPR84 (0.48) | TSHR | |
| SCHEMBL21134014 | 0.79 | CA12 (0.35) | TSHR | |
| SCHEMBL11363078 | 0.79 | GPR84 (0.48) | TSHR | |
| SCHEMBL15153583 | 0.79 | GPR84 (0.48) | TSHR | |
| SCHEMBL8402045 | 0.79 | GPR84 (0.48) | TSHR | |
| SCHEMBL3501372 | 0.79 | GPR84 (0.48) | TSHR | |
| SCHEMBL2818859 | 0.79 | GPR84 (0.48) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197867-B1 | DINITRILE PROCESSING AIDS | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-03-06 | — | — | US | claimed |
| US-6197867-B1 | DINITRILE PROCESSING AIDS | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-03-06 | — | — | US | disclosed |
| EP-0965613-A1 | Rubber compositions containing organo-nitriles | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-12-22 | — | — | EP | disclosed |