Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.35 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.35 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.35 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8818204 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MAPTMEN1USP2POLB | |
| SCHEMBL7901705 | 0.89 | ALDH1A1 (0.37) | ALDH1A1MAPTMEN1USP2POLB | |
| SCHEMBL1720755 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1USP2POLB | |
| SCHEMBL4287942 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1USP2POLB | |
| SCHEMBL4287947 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1USP2POLB | |
| SCHEMBL1720756 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MAPTMEN1USP2POLB | |
| SCHEMBL4284504 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAPTMEN1USP2POLB | |
| SCHEMBL3467883 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MAPTMEN1USP2POLB | |
| SCHEMBL15414470 | 0.76 | ALDH1A1 (0.45) | ALDH1A1MEN1USP2POLBKMT2A | |
| SCHEMBL13649179 | 0.76 | ALDH1A1 (0.45) | ALDH1A1MEN1USP2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197963-B1 | TETRAHYDROPYRAN DERIVATIVES; PROTEIN G, SOMATOSTATIN, AND NATURAL KILLER CELL RECEPTOR ANTAGONISTS OR MIMETICS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2001-03-06 | — | — | US | disclosed |
| US-5811512-A | BINDING TO G-PROTEIN-LINKED RECEPTORS, SUBSTANCE P RECEPTOR; HORMONE INHIBITORS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-09-22 | — | — | US | disclosed |
| US-5552534-A | COMPOUNDS FOR CROSS REACTION WITH PEPTIDES FOR BINDING G PROTEIN | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1996-09-03 | — | — | US | disclosed |