Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.34 |
| ▸ | LGALS9 | O00182 | 2/20 | 0.34 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.34 |
| ▸ | LGALS7; LGALS7B | P47929 | 2/20 | 0.34 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8818204 | 0.89 | ALDH1A1 (0.38) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL7901701 | 0.89 | ALDH1A1 (0.38) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL4287947 | 0.81 | ALDH1A1 (0.43) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL1720756 | 0.81 | ALDH1A1 (0.41) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL1720755 | 0.81 | ALDH1A1 (0.42) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL4287942 | 0.80 | ALDH1A1 (0.44) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL4284504 | 0.77 | ALDH1A1 (0.41) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL3467884 | 0.76 | ALDH1A1 (0.37) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL3467883 | 0.74 | ALDH1A1 (0.37) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL7901697 | 0.73 | PTPN1 (0.47) | POLBMEN1USP2KMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197963-B1 | TETRAHYDROPYRAN DERIVATIVES; PROTEIN G, SOMATOSTATIN, AND NATURAL KILLER CELL RECEPTOR ANTAGONISTS OR MIMETICS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2001-03-06 | — | — | US | disclosed |
| US-5811512-A | BINDING TO G-PROTEIN-LINKED RECEPTORS, SUBSTANCE P RECEPTOR; HORMONE INHIBITORS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-09-22 | — | — | US | disclosed |
| WO-1997028172-A1 | NON-PEPTIDE PEPTIDOMIMETICS AND RELATED CYCLIC HEXAPEPTIDES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1997-08-07 | — | — | WO | disclosed |
| US-5552534-A | COMPOUNDS FOR CROSS REACTION WITH PEPTIDES FOR BINDING G PROTEIN | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1996-09-03 | — | — | US | disclosed |