Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 7/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904729 | 0.88 | CA2 (0.50) | GAALMNAPTGS1PTGS2CA2 | |
| SCHEMBL2851142 | 0.88 | GAA (0.51) | GAALMNAPTGS1PTGS2CA2 | |
| SCHEMBL1808166 | 0.88 | GAA (0.51) | GAALMNAPTGS1PTGS2CA2 | |
| SCHEMBL1808168 | 0.86 | GAA (0.54) | GAALMNAPTGS1PTGS2CA2 | |
| SCHEMBL11516151 | 0.86 | GAA (0.50) | GAALMNAPTGS1PTGS2CA2 | |
| SCHEMBL1808413 | 0.85 | GAA (0.49) | GAALMNAPTGS1PTGS2CA2 | |
| SCHEMBL17689140 | 0.84 | SMN1; SMN2 (0.62) | LMNAPTGS2POLBTSHRMAPK1 | |
| SCHEMBL1808414 | 0.83 | GAA (0.51) | GAALMNAPTGS1PTGS2CA2 | |
| SCHEMBL12545632 | 0.83 | GAA (0.57) | GAALMNAPTGS1PTGS2CA2 | |
| SCHEMBL24478022 | 0.82 | GABRA1 (0.49) | GAALMNAPTGS1PTGS2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |