Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5555898 | 0.94 | CYP1A2 (0.41) | CDC7ALDH1A1ADORA3ADORA1ADORA2A | |
| SCHEMBL15958411 | 0.94 | ALDH1A1 (0.39) | CDC7ALDH1A1ADORA3ADORA1MEN1 | |
| SCHEMBL954434 | 0.88 | ABCB1 (0.41) | CDC7ALDH1A1ADORA3ADORA1ADORA2A | |
| SCHEMBL5555416 | 0.87 | SMPD3 (0.41) | CDC7ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL12293879 | 0.87 | ABCB1 (0.42) | CDC7ALDH1A1ADORA3ADORA1ADORA2A | |
| SCHEMBL2680751 | 0.87 | ABCB1 (0.40) | CDC7ALDH1A1ADORA3ADORA1ADORA2A | |
| SCHEMBL64690 | 0.87 | ABCB1 (0.42) | CDC7ALDH1A1ADORA3ADORA1ADORA2A | |
| SCHEMBL7901976 | 0.87 | CDC7 (0.38) | CDC7ALDH1A1ADORA3ADORA1ADORA2A | |
| SCHEMBL7907604 | 0.86 | HPGD (0.44) | PSDALDH1A1ADORA3MEN1KMT2A | |
| SCHEMBL2681332 | 0.83 | ABCB1 (0.38) | CDC7ALDH1A1ADORA3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204266-B1 | TREATING INFLAMMATION OR CANCER SENSITIVITY BY ADMINISTERING A PYRAZINE DERIVATIVE IN A COSMETIC OR FOOD CARRIER TO EXHIBIT AN ANTIOXIDANT EFFECT | UNIVERSITE CATHOLIQUE DE LOUVAIN HALLES UNIVERSITAIRES (BE) | 2001-03-20 | — | — | US | claimed |
| US-6204266-B1 | TREATING INFLAMMATION OR CANCER SENSITIVITY BY ADMINISTERING A PYRAZINE DERIVATIVE IN A COSMETIC OR FOOD CARRIER TO EXHIBIT AN ANTIOXIDANT EFFECT | UNIVERSITE CATHOLIQUE DE LOUVAIN HALLES UNIVERSITAIRES (BE) | 2001-03-20 | — | — | US | disclosed |