Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64690 | 0.99 | ABCB1 (0.42) | ABCB1CDC7ALDH1A1ADORA3ADORA1 | |
| SCHEMBL12293879 | 0.99 | ABCB1 (0.42) | ABCB1CDC7ALDH1A1ADORA3ADORA1 | |
| SCHEMBL2680751 | 0.97 | ABCB1 (0.40) | ABCB1CDC7ALDH1A1ADORA3ADORA1 | |
| SCHEMBL29887519 | 0.95 | CDC7 (0.43) | ABCB1CDC7ALDH1A1ADORA3ADORA1 | |
| SCHEMBL10196910 | 0.94 | PARP1 (0.38) | ABCB1CDC7ALDH1A1ADORA3ADORA1 | |
| SCHEMBL20841749 | 0.94 | ABCB1 (0.39) | ABCB1CDC7ALDH1A1ADORA3ADORA1 | |
| SCHEMBL13401854 | 0.94 | ABCB1 (0.39) | ABCB1CDC7ALDH1A1ADORA3ADORA1 | |
| SCHEMBL20841761 | 0.94 | ABCB1 (0.39) | ABCB1CDC7ALDH1A1ADORA3ADORA1 | |
| SCHEMBL10196941 | 0.94 | ABCB1 (0.39) | ABCB1CDC7ALDH1A1ADORA3ADORA1 | |
| SCHEMBL10196888 | 0.94 | ABCB1 (0.39) | ABCB1CDC7ALDH1A1ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204266-B1 | TREATING INFLAMMATION OR CANCER SENSITIVITY BY ADMINISTERING A PYRAZINE DERIVATIVE IN A COSMETIC OR FOOD CARRIER TO EXHIBIT AN ANTIOXIDANT EFFECT | UNIVERSITE CATHOLIQUE DE LOUVAIN HALLES UNIVERSITAIRES (BE) | 2001-03-20 | — | — | US | claimed |
| US-12606863-B2 | Bioluminescent detection of DNA synthesis | PROMEGA CORPORATION (US) | 2026-04-21 | — | — | US | disclosed |
| EP-4073512-B1 | COMPOSITIONS AND METHODS FOR BIOLUMINESCENT DETECTION USING MULTIFUNCTIONAL PROBES | PROMEGA CORP (US) | 2025-11-12 | — | — | EP | disclosed |
| US-20250264464-A1 | COMPOSITIONS AND METHODS FOR ANALYTE DETECTION USING BIOLUMINESCENCE | PROMEGA CORPORATION | 2025-08-21 | — | — | US | disclosed |
| CN-119955899-A | Compositions, methods and kits for stabilizing coelenterazine and analogs and derivatives thereof | 普洛麦格公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-112996923-B | Compositions and methods for stabilizing coelenterazine and analogs and derivatives thereof | 普洛麦格公司 | 2025-02-18 | — | — | CN | disclosed |
| US-12130292-B2 | Full length kinase activity-conformation reporter | KINCON BIOLABS GMBH (AT) | 2024-10-29 | — | — | US | disclosed |
| WO-2024217576-A1 | FUSION POLYPEPTIDE AND KIT FOR DETECTING PROCALCITONIN AND USE THEREOF | 深圳琅技生命科技有限公司 | 2024-10-24 | — | — | WO | disclosed |
| EP-3964501-B1 | IMIDAZOPYRAZINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND THEIR USES AS LUCIFERINS | PASTEUR INSTITUT (FR) | 2024-09-04 | — | — | EP | disclosed |
| US-12061202-B2 | Compositions and methods for bioluminescent detection using multifunctional probes | PROMEGA CORPORATION (US) | 2024-08-13 | — | — | US | disclosed |
| US-20100105090-A1 | SECRETED LUCIFERASE MLUC7 AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2010-04-29 | — | — | US | disclosed |
| US-7537912-B2 | Methods of measuring luminogenic activity with a protected coelenterazine | PROMEGA CORPORATION (US) | 2009-05-26 | — | — | US | disclosed |
| US-7396655-B2 | Method for enhancing activity of luciferase with fluorescence activity | CHISSO CORPORATION (JP) | 2008-07-08 | — | — | US | disclosed |
| US-7396655-B2 | Method for enhancing activity of luciferase with fluorescence activity | CHISSO CORPORATION (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-1451155-B1 | COMPOSITIONS, METHODS AND KITS PERTAINING TO LUMINESCENT COMPOUNDS | PROMEGA CORP (US) | 2008-07-02 | — | — | EP | disclosed |
| EP-1894933-A2 | Compositions, methods and kits pertaining to luminescent compounds | PROMEGA CORPORATION (US) | 2008-03-05 | — | — | EP | disclosed |
| US-20080050760-A1 | COMPOSITIONS AND METHODS TO CO-LOCALIZE LUMINOPHORES WITH LUMINESCENT PROTEINS | PROMEGA CORPORATION | 2008-02-28 | — | — | US | disclosed |
| US-7268229-B2 | Compounds to co-localize luminophores with luminescent proteins | PROMEGA CORPORATION (US) | 2007-09-11 | — | — | US | disclosed |
| US-7268229-B2 | Compounds to co-localize luminophores with luminescent proteins | PROMEGA CORPORATION (US) | 2007-09-11 | — | — | US | disclosed |
| US-6204266-B1 | TREATING INFLAMMATION OR CANCER SENSITIVITY BY ADMINISTERING A PYRAZINE DERIVATIVE IN A COSMETIC OR FOOD CARRIER TO EXHIBIT AN ANTIOXIDANT EFFECT | UNIVERSITE CATHOLIQUE DE LOUVAIN HALLES UNIVERSITAIRES (BE) | 2001-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12606863-B2 | Bioluminescent detection of DNA synthesis | PCNA, MKI67, POLL | ABCB1 539/4885CDC7 513/4885ALDH1A1 946/4885 |
| US-20100105090-A1 | SECRETED LUCIFERASE MLUC7 AND USE THEREOF | LUC7L2, MRPL37, TCF7 | ABCB1 3223/4885CDC7 526/4885ALDH1A1 3554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.