Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9083583 | 0.86 | ABCC4 (0.45) | APEX1LMNAALKBH5SUCNR1EGLN1 | |
| SCHEMBL6741379 | 0.82 | APEX1 (0.31) | APEX1 | |
| SCHEMBL11231879 | 0.78 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL5954190 | 0.78 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL27976084 | 0.77 | APEX1 (0.48) | APEX1LMNAALKBH5SUCNR1EGLN1 | |
| SCHEMBL11048256 | 0.76 | TSHR (0.31) | MAPTTSHR | |
| SCHEMBL14501467 | 0.76 | — | — | |
| SCHEMBL17072473 | 0.76 | GRM8 (0.42) | APEX1 | |
| SCHEMBL3004711 | 0.76 | — | — | |
| SCHEMBL420429 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078379-B2 | Method for the prevention of mist formation in a device comprising rolls during the coating of flexible media with a crosslinkable liquid silicone composition | ELKEM SILICONES FRANCE SAS (FR) | 2021-08-03 | — | — | US | claimed |
| CN-109952352-B | Method for preventing fogging during coating of flexible supports with crosslinkable liquid silicone compositions in a roll apparatus | 埃肯有机硅法国简易股份公司 | 2021-04-20 | — | — | CN | claimed |
| CN-107429063-B | Organopolysiloxane and method for producing the same | 埃肯有机硅法国简易股份公司 | 2021-03-23 | — | — | CN | claimed |
| EP-3472252-B1 | METHOD FOR THE PREVENTION OF MIST FORMATION IN A DEVICE COMPRISING ROLLS DURING THE COATING OF FLEXIBLE MEDIA WITH A CROSSLINKABLE LIQUID SILICONE COMPOSITION | ELKEM SILICONES FRANCE S A S (FR) | 2020-04-01 | — | — | EP | claimed |
| US-20190249036-A1 | METHOD FOR THE PREVENTION OF MIST FORMATION IN A DEVICE COMPRISING ROLLS DURING THE COATING OF FLEXIBLE MEDIA WITH A CROSSLINKABLE LIQUID SILICONE COMPOSITION | INSTITUT NATIONAL DES SCIENCES APPLIQUÉES (FR) | 2019-08-15 | — | — | US | claimed |
| US-10358541-B2 | Organopolysiloxanes and methods for preparing same | ELKEM SILICONES FRANCE SAS (FR) | 2019-07-23 | — | — | US | claimed |
| CN-109952352-A | Method for preventing fogging during coating of flexible supports with crosslinkable liquid silicone compositions in a roll apparatus | 埃肯有机硅法国简易股份公司 | 2019-06-28 | — | — | CN | claimed |
| EP-3472252-A1 | METHOD FOR THE PREVENTION OF MIST FORMATION IN A DEVICE COMPRISING ROLLS DURING THE COATING OF FLEXIBLE MEDIA WITH A CROSSLINKABLE LIQUID SILICONE COMPOSITION | Elkem Silicones France S.A.S. (FR) | 2019-04-24 | — | — | EP | claimed |
| US-20180265668-A1 | ORGANOPOLYSILOXANES AND METHODS FOR PREPARING SAME | ELKEM SILICONES FRANCE SAS (FR) | 2018-09-20 | — | — | US | claimed |
| CN-107429063-A | Organopolysiloxane and method for producing the same | 蓝星有机硅法国两合公司 | 2017-12-01 | — | — | CN | claimed |
| CN-111909401-B | Bi-component cross-linked medical composite material, preparation method and application thereof | 杭州仪文生物医药有限公司 | 2021-11-16 | — | — | CN | disclosed |
| US-11078379-B2 | Method for the prevention of mist formation in a device comprising rolls during the coating of flexible media with a crosslinkable liquid silicone composition | ELKEM SILICONES FRANCE SAS (FR) | 2021-08-03 | — | — | US | disclosed |
| CN-109952352-B | Method for preventing fogging during coating of flexible supports with crosslinkable liquid silicone compositions in a roll apparatus | 埃肯有机硅法国简易股份公司 | 2021-04-20 | — | — | CN | disclosed |
| CN-107429063-B | Organopolysiloxane and method for producing the same | 埃肯有机硅法国简易股份公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-111909401-A | Bi-component cross-linked medical composite material, preparation method and application thereof | 杭州仪文生物医药有限公司 | 2020-11-10 | — | — | CN | disclosed |
| US-6193953-B1 | FOR ENHANCING THE ULTRASOUND IMAGE OF A TISSUE OR ORGAN | MOLECULAR BIOSYSTEMS, INC. | 2001-02-27 | — | — | US | disclosed |
| US-6083484-A | CONSIST OF LIQUID AND/OR GAS CORE MATERIAL WHICH IS ENCAPSULATED BY A BIOCOMPATIBLE, TANNED PROTEIN SHELL WHEREIN THE PROTEIN IS CROSSLINKED VIA CHROMIUM-CONTAINING POLYNUCLEAR COORDINATION COMPLEXES | MOLECULAR BIOSYSTEMS, INC. (US) | 2000-07-04 | — | — | US | disclosed |
| EP-0932419-A2 | STABILIZED MICROPARTICLES AND THEIR USE AS ULTRASOUND CONTRAST AGENTS | MOLECULAR BIOSYSTEMS, INC. (US) | 1999-08-04 | — | — | EP | disclosed |
| WO-1998016257-A2 | STABILIZED MICROPARTICLES AND THEIR USE AS ULTRASOUND CONTRAST AGENTS | MOLECULAR BIOSYSTEMS, INC. (US) | 1998-04-23 | — | — | WO | disclosed |
| US-5502174-A | Reactive dyestuffs based on a substituted barbituric acid | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10358541-B2 | Organopolysiloxanes and methods for preparing same | IDUA, MAN2B1, ALG1 | APEX1 3383/4885LMNA 273/4885ALKBH5 2227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.