Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17822721 | 0.91 | ABCC4 (0.52) | ABCC4MAPTLMNASLC22A6TSHR | |
| SCHEMBL7901994 | 0.86 | APEX1 (0.52) | ABCC4MAPTLMNASLC22A6APEX1 | |
| SCHEMBL3327735 | 0.80 | — | — | |
| SCHEMBL9620929 | 0.80 | ALDH1A1 (0.39) | TSHRALDH1A1 | |
| SCHEMBL776640 | 0.77 | NPC1 (0.36) | MAPTLMNANPSR1ALDH1A1 | |
| SCHEMBL1283388 | 0.77 | NPC1 (0.36) | MAPTLMNANPSR1ALDH1A1 | |
| SCHEMBL14987786 | 0.75 | TSHR (0.52) | LMNATSHRKMT2AALDH1A1 | |
| SCHEMBL14987781 | 0.75 | LMNA (0.38) | MAPTLMNATSHRALDH1A1 | |
| SCHEMBL2135110 | 0.75 | NPC1 (0.35) | MAPTLMNANPSR1ALDH1A1 | |
| SCHEMBL2136773 | 0.75 | NPC1 (0.35) | MAPTLMNANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502174-A | Reactive dyestuffs based on a substituted barbituric acid | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |