SCHEMBL7902

SCHEMBL7902

c1cnn(-c2cc[nH]n2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 3/20 0.47
NOTUM Q6P988 1/20 0.41
NPC1 O15118 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
GLA P06280 1/20 0.41
RAB9A P51151 1/20 0.41
LMNA P02545 2/20 0.40
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
G6PD P11413 1/20 0.38
MAPK1 P28482 2/20 0.38
GRM5 P41594 4/20 0.36
HTT P42858 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
NLRP3 Q96P20 1/20 0.35
TDO2 P48775 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11433853 0.72 NOTUM (0.41) NOTUM
SCHEMBL30193794 0.72 LMNA (0.44) ALDH1A1KDM4ENOTUMNPC1SMN1; SMN2
SCHEMBL31609349 0.71 KDM4E (0.46) ALDH1A1KDM4ENOTUMNPC1SMN1; SMN2
SCHEMBL199306 0.70 ALDH1A1 (0.65) ALDH1A1KDM4ENOTUMNPC1SMN1; SMN2
SCHEMBL3791452 0.70 ALDH1A1 (0.31) ALDH1A1MAPT
SCHEMBL28111156 0.70 ALDH1A1 (0.46) ALDH1A1KDM4ENOTUMNPC1SMN1; SMN2
SCHEMBL31519065 0.68 ALDH1A1 (0.63) ALDH1A1KDM4ENOTUMNPC1SMN1; SMN2
SCHEMBL28812535 0.68 ALDH1A1 (0.63) ALDH1A1KDM4ENOTUMNPC1SMN1; SMN2
SCHEMBL2191243 0.68 CA12 (0.41)
SCHEMBL1838766 0.68 ALDH1A1 (0.47) ALDH1A1KDM4ENOTUMNPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 564 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040778-A Zinc metal organic framework material based on pyridine functionalized pyrazole ligand, preparation and application thereof 北京工业大学 2025-05-27 CN claimed
CN-119638627-A Bipyrazole energetic compound and preparation method thereof 西北大学 2025-03-18 CN claimed
CN-221825827-U Crude product dryer for continuous dipyrazole 江苏优普生物化学科技股份有限公司 2024-10-11 CN claimed
CN-115322153-B Bipyrazole energetic compound or energetic salt and preparation method thereof 北京理工大学 2024-06-14 CN claimed
CN-118084791-A High-energy-density compound based on polynitrobenzene bipyrazole and synthesis method thereof 南京理工大学 2024-05-28 CN claimed
EP-4359401-A1 PROCESS FOR PREPARING EGFR INHIBITORS Blueprint Medicines Corporation (US) 2024-05-01 EP claimed
CN-117645618-A Novel heptanuclear copper pyrazole complex, preparation and application of catechol oxidase activity 郑州师范学院 2024-03-05 CN claimed
CN-117186122-A Seven-core copper pyrazole complex, and preparation method and application thereof 郑州师范学院 2023-12-08 CN claimed
CN-114029090-B Preparation method of photocatalyst for removing heavy metals in sewage 中国矿业大学 2023-11-03 CN claimed
CN-111072721-B Compound containing bipyrazole ring, intermediate and application thereof 联化科技(上海)有限公司 2023-05-26 CN claimed
US-5840653-A HERBICIDES HOECHST SCHERING AGREVO GMBH (DE) 1998-11-24 US claimed
WO-1998006702-A1 SUBSTITUTED 1-(3-PYRAZOLYL)-PYRAZOLES BAYER AKTIENGESELLSCHAFT (DE) 1998-02-19 WO claimed
WO-1998003506-A1 SUBSTITUTED PYRAZOLYL-PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS AGENTS WITH A HERBICIDAL EFFECT HOECHST SCHERING AGREVO GMBH (DE) 1998-01-29 WO claimed
WO-1997046536-A1 SUBSTITUTED PYRAZOLYL-PYRAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES HOECHST SCHERING AGREVO GMBH (DE) 1997-12-11 WO claimed
EP-0643700-B1 NEW SUBSTITUTED PYRAZOLYLPYRAZOLES, PROCESSES FOR THEIR PREPARATION, AS WELL AS INTERMEDIATES, AND THEIR USE AS HERBICIDES HOECHST SCHERING AGREVO GMBH (DE) 1996-09-11 EP claimed
US-5405829-A Substituted pyrazolypyrazoles and their use as herbicides SCHERING AKTIENGESELLSCHAFT (DE) 1995-04-11 US claimed
EP-0643700-A1 NEW SUBSTITUTED PYRAZOLYLPYRAZOLES, PROCESSES FOR THEIR PREPARATION, AS WELL AS INTERMEDIATES, AND THEIR USE AS HERBICIDES. SCHERING AG (DE) 1995-03-22 EP claimed
CN-1073440-A The pyrazolyl-pyrazole of new replacement, its preparation method, and their intermediate and they are as the purposes of weedicide SCHERING AG (DE) 1993-06-23 CN claimed
WO-1993010100-A1 NEW SUBSTITUTED PYRAZOLYLPYRAZOLES, PROCESSES FOR THEIR PREPARATION, AS WELL AS INTERMEDIATES, AND THEIR USE AS HERBICIDES SCHERING AKTIENGESELLSCHAFT (DE) 1993-05-27 WO claimed
EP-0542388-A1 New substituted pyrazolylpyrazoles, processes for their preparation, as well as intermediates, and their use as herbicides SCHERING AKTIENGESELLSCHAFT (DE) 1993-05-19 EP claimed