Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7903670 | 0.74 | TSHR (0.36) | TSHRHTR2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL5089860 | 0.73 | GPR3 (0.32) | — | |
| SCHEMBL8163122 | 0.68 | HTR2A (0.40) | TSHRHTR2A | |
| SCHEMBL8857444 | 0.66 | HTR2A (0.38) | TSHRHTR2AMEN1LMNACYP3A4 | |
| Hydrochloric Acid SCHEMBL650445 | 0.66 | POLB (0.31) | — | |
| SCHEMBL6264879 | 0.66 | HTR2A (0.52) | TSHRHTR2AMAPT | |
| SCHEMBL8857418 | 0.65 | HTR2A (0.37) | TSHRHTR2AMEN1LMNACYP3A4 | |
| SCHEMBL8857074 | 0.64 | HTR2A (0.36) | TSHRHTR2AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6908379 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL6915304 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197902-B1 | Syndio-isoblock polymer and process for its preparation | TARGOR GMBH (DE) | 2001-03-06 | — | — | US | disclosed |