Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26328504 | 0.82 | CA12 (0.35) | DGAT1CA12CA14CA1CA2 | |
| SCHEMBL5706172 | 0.73 | DGAT1 (0.39) | DGAT1CA12CA14CA1CA2 | |
| SCHEMBL7277029 | 0.71 | NOS1 (0.36) | DGAT1CA12CA14CA1CA2 | |
| SCHEMBL17093890 | 0.71 | NOS1 (0.36) | DGAT1CA12CA14CA1CA2 | |
| SCHEMBL3890536 | 0.71 | CA12 (0.34) | DGAT1CA12CA14CA1CA2 | |
| SCHEMBL17093771 | 0.71 | NOS1 (0.36) | DGAT1CA12CA14CA1CA2 | |
| SCHEMBL7277018 | 0.71 | CA12 (0.34) | DGAT1CA12CA14CA1CA2 | |
| SCHEMBL7361092 | 0.70 | TSHR (0.44) | DGAT1CA12CA14CA1CA2 | |
| SCHEMBL18206813 | 0.70 | TSHR (0.44) | DGAT1CA12CA14CA1CA2 | |
| SCHEMBL7361094 | 0.70 | TSHR (0.44) | DGAT1CA12CA14CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159255-A2 | BIS(1,3-DIHYDROXY-PROP-2-YL)AMINE AND DERIVATIVES THEREOF IN THE MANUFACTURE OF POLYMERS | ISIS INNOVATION LIMITED (GB) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000055111-A2 | BIS(1,3-DIHYDROXY-PROP-2-YL)AMINE AND DERIVATIVES THEREOF IN THE MANUFACTURE OF POLYMERS | ISIS INNOVATION LIMITED (GB) | 2000-09-21 | — | — | WO | disclosed |