Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 7/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.49 |
| ▸ | MTOR | P42345 | 4/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807046 | 0.93 | PIK3CG (0.44) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL807470 | 0.91 | PIK3CG (0.55) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL10274897 | 0.87 | PIK3CG (0.54) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL790802 | 0.86 | PIK3CG (0.64) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL789741 | 0.84 | PI4KA (0.46) | PI4KAPIK3CGPIK3CAMTORALDH1A1 | |
| SCHEMBL807247 | 0.83 | PIK3CG (0.48) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL791568 | 0.83 | PI4KA (0.43) | PI4KAPIK3CGPIK3CAMTORALDH1A1 | |
| SCHEMBL10277708 | 0.83 | PI4KA (0.51) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL807155 | 0.83 | PIK3CG (0.62) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL806791 | 0.82 | PI4KA (0.43) | PI4KAPIK3CGPIK3CAMTORALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |