Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 3/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791568 | 0.89 | PI4KA (0.43) | PI4KAPIK3CGRAB9AALDH1A1KDM4E | |
| SCHEMBL807111 | 0.89 | RAB9A (0.46) | PI4KAPIK3CGRAB9AALDH1A1KDM4E | |
| SCHEMBL789808 | 0.89 | PIK3CG (0.44) | PI4KAPIK3CGRAB9AALDH1A1KDM4E | |
| SCHEMBL807161 | 0.89 | PIK3C3 (0.49) | PI4KAPIK3CGRAB9AALDH1A1KDM4E | |
| SCHEMBL790545 | 0.88 | PIK3C3 (0.44) | PI4KAPIK3CGRAB9AALDH1A1KDM4E | |
| SCHEMBL12474809 | 0.88 | PI4KA (0.41) | PI4KAPIK3CGRAB9AALDH1A1KDM4E | |
| SCHEMBL807023 | 0.88 | PIK3CG (0.49) | PI4KAPIK3CGRAB9APIK3C3PIK3CA | |
| SCHEMBL789820 | 0.87 | ALDH1A1 (0.43) | PI4KAPIK3CGRAB9AALDH1A1KDM4E | |
| SCHEMBL789741 | 0.87 | PI4KA (0.46) | PI4KAPIK3CGRAB9AALDH1A1KDM4E | |
| SCHEMBL807010 | 0.87 | SMN1; SMN2 (0.44) | PI4KAPIK3CGRAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |