Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902644 | 0.86 | HTR1B (0.31) | KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7896418 | 0.82 | RAB9A (0.46) | RAB9AMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL7905953 | 0.80 | RAB9A (0.45) | RAB9AMAPTLMNASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL7908541 | 0.79 | RAB9A (0.44) | RAB9AMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL7896538 | 0.79 | RAB9A (0.43) | RAB9AMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL7896449 | 0.78 | HTT (0.45) | RAB9AMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL7908490 | 0.77 | FLT3 (0.42) | RAB9AMAPTLMNANPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7904720 | 0.76 | RAB9A (0.36) | RAB9AMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL7905792 | 0.74 | NPC1 (0.49) | RAB9AMAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL7896414 | 0.74 | HRH3 (0.39) | RAB9AMAPTLMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |