Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896422 | 0.88 | FLT3 (0.41) | FLT3HRH3MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL7904730 | 0.87 | FLT3 (0.40) | FLT3CYP1A2BACE1LMNAUSP2 | |
| SCHEMBL7908577 | 0.85 | FLT3 (0.39) | FLT3CYP1A2BACE1LMNAUSP2 | |
| SCHEMBL7905726 | 0.84 | FLT3 (0.40) | FLT3ALDH1A1USP2 | |
| SCHEMBL7904450 | 0.83 | FLT3 (0.40) | FLT3ALDH1A1USP2 | |
| SCHEMBL7896418 | 0.78 | RAB9A (0.46) | HRH3MAPK1ALDH1A1LMNARAB9A | |
| SCHEMBL7896411 | 0.78 | USP2 (0.43) | FLT3HRH3MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL7902307 | 0.77 | RAB9A (0.40) | MAPK1ALDH1A1LMNARAB9AMAPT | |
| SCHEMBL7905953 | 0.77 | RAB9A (0.45) | HRH3ALDH1A1LMNARAB9AMAPT | |
| Hydrochloric Acid SCHEMBL7908541 | 0.76 | RAB9A (0.44) | HRH3ALDH1A1LMNARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191152-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | EGIS GYÓGYSZERGYAR RT. (HU) | 2001-02-20 | — | — | US | disclosed |