Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902484 | 1.00 | SPHK1 (0.45) | SPHK1SPHK2SIGMAR1MEN1TP53 | |
| SCHEMBL7902476 | 1.00 | SPHK1 (0.45) | SPHK1SPHK2SIGMAR1MEN1TP53 | |
| SCHEMBL7902481 | 1.00 | SPHK1 (0.45) | SPHK1SPHK2SIGMAR1MEN1TP53 | |
| SCHEMBL8853239 | 0.94 | SPHK1 (0.40) | SPHK1SPHK2SIGMAR1MEN1TP53 | |
| SCHEMBL15043588 | 0.90 | SPHK1 (0.43) | SPHK1SPHK2SIGMAR1MEN1TP53 | |
| SCHEMBL7912569 | 0.82 | ESR2 (0.38) | SPHK1SPHK2CYP3A4 | |
| SCHEMBL7912562 | 0.82 | ESR2 (0.38) | SPHK1SPHK2CYP3A4 | |
| SCHEMBL28979499 | 0.80 | SPHK1 (0.64) | SPHK1SPHK2MEN1KMT2A | |
| SCHEMBL28979501 | 0.80 | SPHK1 (0.64) | SPHK1SPHK2MEN1KMT2A | |
| SCHEMBL18808093 | 0.80 | SPHK1 (0.35) | SPHK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174456-B1 | STABILITY, LOW VISCOSITY AND HIGH TRANSITION TEMPERATURE OF THE ISOTROPIC PHASE | CHISSO CORPORATION (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0857708-A1 | LIQUID CRYSTAL COMPOUNDS HAVING SUBSTITUTED ALKYL GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 1998-08-12 | — | — | EP | disclosed |