Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15043588 | 0.96 | SPHK1 (0.43) | SPHK1SPHK2SIGMAR1MEN1TP53 | |
| SCHEMBL7902481 | 0.94 | SPHK1 (0.45) | SPHK1SPHK2SIGMAR1MEN1TP53 | |
| SCHEMBL7902476 | 0.94 | SPHK1 (0.45) | SPHK1SPHK2SIGMAR1MEN1TP53 | |
| SCHEMBL7902487 | 0.94 | SPHK1 (0.45) | SPHK1SPHK2SIGMAR1MEN1TP53 | |
| SCHEMBL7902484 | 0.94 | SPHK1 (0.45) | SPHK1SPHK2SIGMAR1MEN1TP53 | |
| SCHEMBL7912562 | 0.84 | ESR2 (0.38) | SPHK1SPHK2CYP3A4 | |
| SCHEMBL7912569 | 0.84 | ESR2 (0.38) | SPHK1SPHK2CYP3A4 | |
| SCHEMBL7910962 | 0.84 | SPHK1 (0.37) | SPHK1SPHK2 | |
| SCHEMBL7910953 | 0.84 | SPHK1 (0.37) | SPHK1SPHK2 | |
| SCHEMBL7910956 | 0.84 | SPHK1 (0.37) | SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9077703-A | — | — | None | — | — | JP | disclosed |
| JP-H0977703-A | LIQUID CRYSTAL COMPOUND CONTAINING HALOGEN ATOM AND ALKENYL GROUP AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP | 1997-03-25 | — | — | JP | disclosed |