Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ILK | Q13418 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599593 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HSD17B10GAAMAPTHPGD | |
| SCHEMBL7902863 | 0.80 | KDM4C (0.53) | KDM4CTSHRALDH1A1HSD17B10GAA | |
| SCHEMBL4650087 | 0.77 | KDM4C (0.50) | KDM4CTSHRALDH1A1HSD17B10GAA | |
| SCHEMBL11205400 | 0.74 | KDM4C (0.47) | KDM4CALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL6993979 | 0.73 | KDM4C (0.65) | KDM4CTSHRALDH1A1HSD17B10GAA | |
| SCHEMBL11472383 | 0.73 | GAA (0.49) | KDM4CTSHRALDH1A1GAAMAPT | |
| SCHEMBL20471480 | 0.73 | KDM4C (0.46) | KDM4CTSHRALDH1A1HSD17B10GAA | |
| SCHEMBL28954059 | 0.72 | KDM4C (0.49) | KDM4CTSHRALDH1A1HSD17B10GAA | |
| SCHEMBL8474076 | 0.72 | KDM4C (0.41) | KDM4CTSHRALDH1A1HSD17B10GAA | |
| SCHEMBL9038036 | 0.72 | KDM4C (0.49) | KDM4CTSHRALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10220030-B2 | Amino-quinolines as kinase inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-03-05 | — | — | US | disclosed |
| US-20180085365-A1 | AMINO-QUINOLINES AS KINASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-03-29 | — | — | US | disclosed |
| US-20180085365-A1 | AMINO-QUINOLINES AS KINASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-03-29 | — | — | US | disclosed |
| EP-0722446-A1 | DISTAMYCIN A ANALOGUES AS ANTITUMOUR OR ANTIVIRAL AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 1996-07-24 | — | — | EP | disclosed |
| WO-1996005196-A1 | DISTAMYCIN A ANALOGUES AS ANTITUMOUR OR ANTIVIRAL AGENTS | PHARMACIA S.P.A. (IT) | 1996-02-22 | — | — | WO | disclosed |
| EP-0138622-A2 | 8-substituted pyrazolopentathiepins and related compounds | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10220030-B2 | Amino-quinolines as kinase inhibitors | ABL1, MAP3K3, MAP3K7 | KDM4C 707/4885TSHR 1809/4885ALDH1A1 3743/4885 |
| US-20180085365-A1 | AMINO-QUINOLINES AS KINASE INHIBITORS | ABL1, MAP3K3, MAP3K7 | KDM4C 707/4885TSHR 1809/4885ALDH1A1 3743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.