Sugi Predict

Sugi Predict / Compounds / SCHEMBL7903010

SCHEMBL7903010

SCHEMBL7903010

CCCc1ccc(OC(C)C)cc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.53
▸ KDM4E B2RXH2 1/20 0.49
▸ PPARG P37231 1/20 0.47
▸ PPARA Q07869 1/20 0.47
▸ CYP1A2 P05177 1/20 0.47
▸ GAA P10253 1/20 0.47
▸ CYP2D6 P10635 1/20 0.47
▸ CYP2C19 P33261 1/20 0.47
▸ ACACB O00763 2/20 0.46
▸ THRB P10828 1/20 0.46
▸ ALDH1A3 P47895 1/20 0.45
▸ ALDH1A1 P00352 1/20 0.45
▸ LMNA P02545 1/20 0.45
▸ KMT2A Q03164 1/20 0.44
▸ TSPO P30536 1/20 0.43
▸ PARP10 Q53GL7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5174164 0.89 BCHE (0.47) POLBKDM4ELMNA
SCHEMBL13348593 0.88 POLB (0.50) POLBKDM4EPPARACYP1A2GAA
SCHEMBL27729576 0.85 ACACB (0.50) POLBPPARGPPARAACACBTHRB
SCHEMBL26939981 0.84 ESR1 (0.53) POLBKDM4EPPARATHRBALDH1A1
SCHEMBL19058769 0.84 ESR1 (0.53) POLBKDM4EPPARATHRBALDH1A1
SCHEMBL8734047 0.84 ESR1 (0.53) POLBKDM4EPPARATHRBALDH1A1
SCHEMBL8719660 0.83 PPARG (0.45) POLBPPARGPPARAACACBTHRB
SCHEMBL4137878 0.83 PPARG (0.49) POLBPPARGPPARAACACBTHRB
SCHEMBL23474900 0.83 ACACB (0.51) POLBKDM4EGAAACACBALDH1A3
SCHEMBL805120 0.82 POLB (0.57) POLBKDM4EPPARGPPARACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066047-A1 ANTIBODY-DRUG CONJUGATES COMPRISING A CYCLIC DINUCLEOTIDE TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-02-29 — — US disclosed
WO-2023154291-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMACEUTICALS INCORPORATED (US) 2023-08-17 — — WO disclosed
US-20210137962-A9 CYCLIC DINUCLEOTIDE TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2021-05-13 — — US disclosed
US-10980825-B2 Cyclic dinucleotide TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2021-04-20 — — US disclosed
US-20190192549-A1 CYCLIC DINUCLEOTIDE TAKEDA PHARMACEUTICALS CO (JP) 2019-06-27 — — US disclosed
US-9239408-B2 Colored photosensitive composition ADEKA CORPORATION (JP) 2016-01-19 — — US disclosed
US-8962244-B2 Compounds for modulating RNA binding proteins and uses therefor UNIVERSITY OF MASSACHUSETTS (US) 2015-02-24 — — US disclosed
US-8958165-B2 Cyanine compound and optical filter and optical recording material containing same ADEKA CORPORATION (JP) 2015-02-17 — — US disclosed
US-20130306920-A1 COLORED PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-11-21 — — US disclosed
US-20130217685-A1 COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR UNIVERSITY OF MASSACHUSETTS (US) 2013-08-22 — — US disclosed
US-20100003445-A1 CYANINE COMPOUND AND OPTICAL FILTER AND OPTICAL RECORDING MATERIAL CONTAINING SAME ADEKA CORPORATION (JP) 2010-01-07 — — US disclosed
WO-2009076747-A1 VIRAL POLYMERASE INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-06-25 — — WO disclosed
WO-2008134734-A2 ENCAPSULATED CONTRAST AGENTS INTEZYNE TECHNOLOGIES, INC. (US) 2008-11-06 — — WO disclosed
WO-2008134731-A1 HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS INTEZYNE TECHNOLOGIES, INC. (US) 2008-11-06 — — WO disclosed
WO-2008106657-A2 ENCAPSULATED AMYLOID-BETA PEPTIDES INTEZYNE TECHNOLOGIES, INC. (US) 2008-09-04 — — WO disclosed
CN-101225219-A Laser-weldable resin composition and molded product WINTECH POLYMER LTD (JP) 2008-07-23 — — CN disclosed
US-20080146569-A1 Nicotinamide Derivatives PFIZER INC. 2008-06-19 — — US disclosed
US-20080125524-A1 Optical Filter ADEKA CORPORATION (JP) 2008-05-29 — — US disclosed
CN-101123962-A Inducible nitric oxide synthase dimerization inhibitors KALYPSYS INC (US) 2008-02-13 — — CN disclosed
CN-1122348-A Stable, aqueous epoxy resin dispersion, process for its preparation, and its use HOECHST AG (DE) 1996-05-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240066047-A1 ANTIBODY-DRUG CONJUGATES COMPRISING A CYCLIC DINUCLEOTIDE STING1, TLR9, CGAS POLB 485/4885KDM4E 3337/4885PPARG 4681/4885
US-20130217685-A1 COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR TIA1, ZFP3, RBM3 POLB 1362/4885KDM4E 3175/4885PPARG 2390/4885
US-20210137962-A9 CYCLIC DINUCLEOTIDE STING1, CGAS, MAVS POLB 159/4885KDM4E 3734/4885PPARG 3482/4885
US-10980825-B2 Cyclic dinucleotide STING1, CGAS, MAVS POLB 159/4885KDM4E 3734/4885PPARG 3482/4885
US-20190192549-A1 CYCLIC DINUCLEOTIDE STING1, CGAS, MAVS POLB 159/4885KDM4E 3734/4885PPARG 3482/4885
US-20100003445-A1 CYANINE COMPOUND AND OPTICAL FILTER AND OPTICAL RECORDING MATERIAL CONTAINING SAME HCN2, CHAT, KCNN2 POLB 4863/4885KDM4E 1453/4885PPARG 4632/4885
US-20080146569-A1 Nicotinamide Derivatives NNT, NAMPT, NADK POLB 2232/4885KDM4E 3026/4885PPARG 147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.