Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRD2 | P25440 | 1/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1803955 | 0.86 | GLO1 (0.42) | CA2CA1CA12CA9BRD4 | |
| SCHEMBL111618 | 0.86 | CA12 (0.52) | CA2MAPTATMCA1CA12 | |
| SCHEMBL7904621 | 0.85 | CA2 (0.52) | CA2MAPTCA1CA12CA9 | |
| SCHEMBL29469901 | 0.85 | CA2 (0.52) | CA2MAPTCA1CA12CA9 | |
| SCHEMBL1803957 | 0.84 | CA2 (0.53) | CA2MAPTCA1CA12CA9 | |
| SCHEMBL6839421 | 0.82 | POLB (0.52) | CA2FFAR4CNR1CNR2MAPT | |
| SCHEMBL1805341 | 0.81 | CA2 (0.43) | CA2CA1CA12CA9BRD4 | |
| SCHEMBL28732668 | 0.81 | CA2 (0.48) | CA2SMN1; SMN2MAPTCA1CA12 | |
| SCHEMBL1805343 | 0.80 | CA2 (0.50) | CA2CA1CA12CA9BRD4 | |
| SCHEMBL27554982 | 0.80 | CA2 (0.42) | CA2CA1CA12CA9BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |