Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FGF1 | P05230 | 2/20 | 0.34 |
| ▸ | FGF2 | P09038 | 2/20 | 0.34 |
| ▸ | VEGFA | P15692 | 2/20 | 0.34 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.34 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898146 | 1.00 | ALDH1A1 (0.41) | ALDH1A1POLBLMNATSHRKMT2A | |
| SCHEMBL7898143 | 1.00 | ALDH1A1 (0.41) | ALDH1A1POLBLMNATSHRKMT2A | |
| SCHEMBL8650408 | 0.89 | ALDH1A1 (0.42) | ALDH1A1POLBLMNATSHRKMT2A | |
| SCHEMBL8672177 | 0.84 | PDPK1 (0.37) | ALDH1A1LMNATSHRKMT2ACYP2D6 | |
| SCHEMBL13130008 | 0.83 | PDPK1 (0.47) | ALDH1A1POLBLMNATSHRKMT2A | |
| SCHEMBL13129987 | 0.83 | PDPK1 (0.47) | ALDH1A1POLBLMNATSHRKMT2A | |
| SCHEMBL13129838 | 0.83 | PDPK1 (0.47) | ALDH1A1POLBLMNATSHRKMT2A | |
| SCHEMBL13129806 | 0.83 | PDPK1 (0.47) | ALDH1A1POLBLMNATSHRKMT2A | |
| SCHEMBL13129911 | 0.83 | PDPK1 (0.47) | ALDH1A1POLBLMNATSHRKMT2A | |
| SCHEMBL13130040 | 0.83 | PDPK1 (0.47) | ALDH1A1POLBLMNATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184365-B1 | 3,4-DI-O,N-PROTECTED-4-AMINO-2,4,6-TRIDEOXY-2-FLUORO-L-TALOPYR ANOSYL IODIDE OR BROMIDE; CHEMICAL INTERMEDIATES FOR PRODUCTION OF NOVEL DAUNOMYCINONE OR ADRIAMYCINONE DERIVATIVES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0848010-A1 | Novel anthracycline derivatives having 4-amino-2,4,6-trideoxy-2-fluoro-alpha-L-talopyranosyl group | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1998-06-17 | — | — | EP | disclosed |