SCHEMBL8650408

SCHEMBL8650408

CC(=O)OC1O[C@@H](C)[C@@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1F

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
PDPK1 O15530 1/20 0.40
MTOR P42345 1/20 0.40
LMNA P02545 2/20 0.39
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
NT5E P21589 1/20 0.37
TSHR P16473 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP2D6 P10635 1/20 0.36
MAPK1 P28482 1/20 0.36
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6219718 0.90 PDPK1 (0.44) ALDH1A1PDPK1MTORLMNANT5E
SCHEMBL7898143 0.89 ALDH1A1 (0.41) ALDH1A1PDPK1MTORLMNACYP2C9
SCHEMBL7898146 0.89 ALDH1A1 (0.41) ALDH1A1PDPK1MTORLMNACYP2C9
SCHEMBL7903019 0.89 ALDH1A1 (0.41) ALDH1A1PDPK1MTORLMNACYP2C9
SCHEMBL13129907 0.88 PDPK1 (0.43) ALDH1A1PDPK1MTORLMNANT5E
SCHEMBL13129920 0.87 ALDH1A1 (0.42) ALDH1A1PDPK1MTORLMNACYP2C9
SCHEMBL2803497 0.87 ALDH1A1 (0.42) ALDH1A1PDPK1MTORLMNACYP2C9
SCHEMBL7899774 0.86 PDPK1 (0.39) PDPK1MTORCYP2C19TSHR
SCHEMBL8382892 0.85 ALDH1A1 (0.38) ALDH1A1PDPK1MTORLMNACYP2C9
SCHEMBL8382890 0.85 ALDH1A1 (0.38) ALDH1A1PDPK1MTORLMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5808018-A Fluorine containing sialyl Lewis X derivatives and synthetic intermediates thereof DAIKIN INDUSTRIES, LTD. (JP) 1998-09-15 US disclosed
EP-0811634-A1 FLUORINATED SIALYL-LEWIS X DERIVATIVES AND INTERMEDIATES FOR SYNTHESIS THEREOF DAIKIN INDUSTRIES, LIMITED (JP) 1997-12-10 EP disclosed