SCHEMBL7903124

SCHEMBL7903124

FC(F)(F)SOc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.41
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.38
CA4 P22748 1/20 0.38
KCNA3 P22001 1/20 0.35
LMNA P02545 1/20 0.34
CA5A P35218 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
PDK2 Q15119 1/20 0.33
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
RAB9A P51151 1/20 0.32
NR1H2 P55055 1/20 0.32
BAX Q07812 1/20 0.32
MAOA P21397 1/20 0.32
KIF11 P52732 1/20 0.32
MAPT P10636 1/20 0.32
ATM Q13315 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18461290 0.77 CA4 (0.42) LTA4HTSHRALDH1A1CA4KCNA3
SCHEMBL2274706 0.73 MAOB (0.43) TSHRALDH1A1LMNACA5ARAB9A
SCHEMBL20431984 0.73 KIF11 (0.39) ALDH1A1LMNAKIF11MAPTL3MBTL1
SCHEMBL5671230 0.72 KDM4E (0.50) LMNAPDK2MAPT
SCHEMBL19568069 0.72
SCHEMBL13211615 0.71 LTA4H (0.50) LTA4HTSHRALDH1A1CA4KCNA3
SCHEMBL361420 0.71 LTA4H (0.50) LTA4HTSHRALDH1A1CA4KCNA3
SCHEMBL1304491 0.69
SCHEMBL24838560 0.67
SCHEMBL9628531 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113574059-A Modified ionic liquids containing a cyclic phosphorus moiety 诺姆斯科技股份有限公司 2021-10-29 CN disclosed
US-6194393-B1 A GLYCOSIDE CONTAINING AN ANOMERIC SULFOXIDE AND NUCLEOPHILIC FUNCTIONAL GROUPS AND HAVING POTENTIAL GLYCOSYL ACCEPTING/DONATING CHARACTERISTICS AND AN ACTIVATING AGENT; RAPID CONSTRUCTION OLIGOSACCHARIDES; GLYCOSYLATION; LIBRARY THE TRUSTEES OF PRINCETON UNIVERSITY 2001-02-27 US disclosed
US-5861492-A LIBRARIES OF SULFOXIDE-SUBSTITUTED GLYCOSIDES WHICH CAN BIND TO OTHER GLYCOSIDES, STEROIDS, AMINO ACIDS, PEPTIDES, LIPIDS OR POLYCYCLIC AROMATIC COMPOUNDS; FOR RAPID, EFFICIENT, SELECTIVE, MULTIPLE GLYCOSYLATION REACTIONS IN ONE STEP THE TRUSTEES OF PRINCETON UNIVERSITY (US) 1999-01-19 US disclosed
US-5792839-A REACTING GLCOSYL DONOR HAVING ANOMERIC SULFOXIDE GROUP AND GLYCOSYL ACCEPTOR AT LOW TEMPERATURE TRUSTEES OF PRINCETON UNIVERSITY (US) 1998-08-11 US disclosed
US-5700916-A INTERMEDIATES FOR FORMING OLIGOSACCHARIDES, INCLUDING 4-HYDROXYTHIOPHENYL-/2-AZIDO-2-DEOXYGLUCO/PYRANOSIDE TRUSTEES OF PRINCETON UNIVERSITY (US) 1997-12-23 US disclosed
US-5635612-A Method of forming multiple glycosidic linkages in a single step THE TRUSTEES OF PRINCETON UNIVERSITY (US) 1997-06-03 US disclosed