Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15196096 | 0.74 | — | — | |
| SCHEMBL746463 | 0.71 | — | — | |
| SCHEMBL22132885 | 0.66 | — | — | |
| SCHEMBL2537422 | 0.65 | — | — | |
| SCHEMBL6205335 | 0.64 | HDAC1 (0.33) | KDM4E | |
| SCHEMBL2534494 | 0.63 | — | — | |
| SCHEMBL13544589 | 0.62 | POLB (0.68) | KDM4EPOLB | |
| SCHEMBL13544858 | 0.62 | POLB (0.50) | POLB | |
| SCHEMBL12517125 | 0.62 | POLB (0.68) | KDM4EPOLB | |
| SCHEMBL18322504 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086646-A1 | SCRIPTAID ISOSTERES AND THEIR USE IN THERAPY | KARUS THERAPEUTICS LIMITED (GB) | 2010-08-05 | — | — | WO | disclosed |