⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9334066 | 0.80 | — | — | |
| SCHEMBL15196096 | 0.80 | — | — | |
| SCHEMBL18951830 | 0.80 | — | — | |
| SCHEMBL1101334 | 0.80 | — | — | |
| SCHEMBL7903258 | 0.71 | KDM4E (0.33) | — | |
| SCHEMBL22132885 | 0.71 | — | — | |
| SCHEMBL5140299 | 0.68 | GABRA1 (0.34) | — | |
| SCHEMBL7853600 | 0.67 | — | — | |
| SCHEMBL3601925 | 0.65 | — | — | |
| SCHEMBL7265383 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497626-B2 | Variant dihydrodipicolinate reductase polypeptide and method of producing L-threonine using the same | CJ CHEILJEDANG CORPORATION (KR) | 2025-12-16 | — | — | US | claimed |
| WO-2025061082-A1 | METHOD FOR PRODUCING SPERMIDINE | 西安卓虹超源生物科技有限公司 | 2025-03-27 | — | — | WO | claimed |
| CN-111770993-B | Modulation of CSR systems to produce lysine and lysine-derived products | 上海凯赛生物技术股份有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-118006528-A | Genetically engineered bacterium for producing tetrahydropyrimidine, preparation method and application | 台州市益善生物技术有限公司 | 2024-05-10 | — | — | CN | claimed |
| US-11781163-B2 | Reducing the accumulation of imines/enamines for the production of amino acids or amino acid-derived products | CATHAY BIOTECH INC. (CN) | 2023-10-10 | — | — | US | claimed |
| CN-111406104-B | Reduction of accumulation of imine/enamine for production of amino acid or amino acid derivative products | 上海凯赛生物技术股份有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-115948396-A | Glutamate dehydrogenase promoter mutant and application thereof | 中国科学院天津工业生物技术研究所 | 2023-04-11 | — | — | CN | claimed |
| CN-115449519-B | Polynucleotide having promoter activity based on dapB gene and use thereof | 中国科学院天津工业生物技术研究所 | 2023-04-07 | — | — | CN | claimed |
| CN-115594886-A | Stabilizer for chlorinated polyethylene for flame-retardant ABS production and preparation method thereof | 潍坊亚星化学股份有限公司（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-115506035-A | Promoter mutant library construction method and promoter mutant library | 中国科学院天津工业生物技术研究所 | 2022-12-23 | — | — | CN | claimed |
| US-20020159976-A1 | Lactobacillus rhamnosus polynucleotides, polypeptides and methods for using them | VIALACTIA BIOSCIENCE (NZ) LIMITED (NZ) | 2002-10-31 | — | — | US | claimed |
| US-20020081673-A1 | Novel nucleotide sequences coding for the glbO gene | MOCKEL BETTINA (DE) | 2002-06-27 | — | — | US | claimed |
| EP-0296316-B1 | 1,4-DIHYDROPYRIDINE ENANTIOMERS | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1993-09-01 | — | — | EP | claimed |
| CN-1070397-A | Dihydropyridine and method for making and medicinal thereof that the indoles sulphonamide replaces | BAYER AG (DE) | 1993-03-31 | — | — | CN | claimed |
| US-4994461-A | Vasodilators; treating cardiovascular disorders | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1991-02-19 | — | — | US | claimed |
| US-4942165-A | Treatment for Alzheimer's disease | ADVANCED BIOLOGICS, INC. (US) | 1990-07-17 | — | — | US | claimed |
| CN-1041758-A | The preparation of 4-aryl dihydropyridine acid amides | BAYER AG (DE) | 1990-05-02 | — | — | CN | claimed |
| CN-1039583-A | 1,4-dihydropyridine threonine derivatives, preparation method, intermediate and medicinal application | BAYER AG (DE) | 1990-02-14 | — | — | CN | claimed |
| CN-88101927-A | Dihydropyridine amides, its preparation method and application pharmaceutically | — | 1988-11-16 | — | — | CN | claimed |
| CN-86108499-A | 1 of novel fluorine, 4-dihydropyridine compounds and their preparation method and as the purposes of medicine | — | 1987-07-15 | — | — | CN | claimed |