Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 11/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3225396 | 0.81 | NOTUM (0.54) | NOTUMKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL29591345 | 0.80 | LIPG (0.48) | LPLLIPG | |
| SCHEMBL29591332 | 0.78 | LPL (0.39) | LPLLIPG | |
| SCHEMBL28521876 | 0.74 | LIPG (0.61) | ALDH1A1HPGDNPC1RAB9ALPL | |
| SCHEMBL20114004 | 0.72 | LPL (0.52) | LPLLIPG | |
| SCHEMBL17694561 | 0.71 | NOTUM (0.78) | NOTUMKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL28543193 | 0.71 | LPL (0.34) | LPLLIPG | |
| SCHEMBL28495477 | 0.71 | LPL (0.34) | LPLLIPG | |
| SCHEMBL18467899 | 0.70 | LPL (0.44) | LPLLIPG | |
| SCHEMBL19905011 | 0.70 | LPL (0.44) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197967-B1 | CYCLIZATION OF 4-CARBOXYPHENYLBORONIC ACID WITH HYDRAZIDE DERIVATIVE; HYDROLYSIS; CATALYTIC ESTERIFICATION | CLARIANT GMBH (DE) | 2001-03-06 | — | — | US | disclosed |