Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905347 | 0.88 | HTR1A (0.32) | HTR1ADRD2 | |
| Tivirapine SCHEMBL377308 | 0.87 | HTR1A (0.31) | HTR1ADRD2 | |
| SCHEMBL7908098 | 0.87 | PARP1 (0.32) | HTR1ADRD2 | |
| Tivirapine SCHEMBL3145162 | 0.87 | HTR1A (0.31) | HTR1ADRD2 | |
| SCHEMBL8844411 | 0.87 | PARP1 (0.33) | HTR1ADRD2 | |
| Tivirapine SCHEMBL8844208 | 0.86 | HTR1A (0.31) | HTR1ADRD2 | |
| SCHEMBL4062423 | 0.81 | HTR1A (0.46) | HTR1ADRD2 | |
| SCHEMBL29624058 | 0.81 | HTR1A (0.46) | HTR1ADRD2 | |
| SCHEMBL599870 | 0.81 | HTR1A (0.46) | HTR1ADRD2 | |
| Tibo SCHEMBL1077005 | 0.74 | GRIN2D (0.31) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371079-A | Administering to inhibit replication of HIV-1 in human cells | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-12-06 | — | — | US | claimed |
| US-6201119-B1 | 2,3,4,5-TETRAHYDRO-1H-1,4-BENZODIAZEPIN-9-AMINE COMPOUNDS USEFUL AS INTERMEDIATES TO ANTIVIRALS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-03-13 | — | — | US | disclosed |
| US-5371079-A | Administering to inhibit replication of HIV-1 in human cells | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-12-06 | — | — | US | disclosed |
| US-5270464-A | Anti-HIV-1 tetrahydroimidazo[1,4]benzodiazepin-2-(thi) ones | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-12-14 | — | — | US | disclosed |