Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tivirapine SCHEMBL377308 | 1.00 | HTR1A (0.31) | HTR1ADRD2 | |
| Tivirapine SCHEMBL8844208 | 0.99 | HTR1A (0.31) | HTR1ADRD2 | |
| SCHEMBL7905545 | 0.90 | HTR1A (0.32) | HTR1ADRD2 | |
| SCHEMBL7905347 | 0.88 | HTR1A (0.32) | HTR1ADRD2 | |
| SCHEMBL7903407 | 0.87 | HTR1A (0.31) | HTR1ADRD2 | |
| SCHEMBL8844411 | 0.87 | PARP1 (0.33) | HTR1ADRD2 | |
| SCHEMBL8844088 | 0.86 | HTR1A (0.32) | HTR1ADRD2 | |
| SCHEMBL8844167 | 0.86 | HTR1A (0.32) | HTR1ADRD2 | |
| SCHEMBL9274799 | 0.85 | HTR1A (0.33) | HTR1ADRD2 | |
| SCHEMBL9695807 | 0.83 | HTR1A (0.30) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| EP-3146048-A2 | NUCLEIC ACIDS ACTING AS DECOYS FOR THE TREATMENT OF LENTIVIRUS INFECTION | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2017-03-29 | — | — | EP | disclosed |
| WO-2015177331-A2 | NUCLEIC ACIDS ACTING AS DECOYS FOR THE TREATMENT OF LENTIVIRUS INFECTION | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2015-11-26 | — | — | WO | disclosed |
| US-20100030530-A1 | METHOD OF SEARCHING FOR LIGAND | ASTELLAS PHARMA INC. (JP) | 2010-02-04 | — | — | US | disclosed |
| EP-2065818-A1 | METHOD OF SEARCHING FOR LIGAND | Astellas Pharma Inc. (JP) | 2009-06-03 | — | — | EP | disclosed |