Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.54 |
| ▸ | RXRA | P19793 | 2/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741430 | 0.91 | RXRA (0.53) | PPARGRXRAPLA2G2A | |
| SCHEMBL7913521 | 0.91 | RXRA (0.53) | PPARGRXRAPLA2G2A | |
| SCHEMBL8741429 | 0.91 | RXRA (0.53) | PPARGRXRAPLA2G2A | |
| SCHEMBL7104435 | 0.85 | PPARG (0.60) | PPARGRXRA | |
| SCHEMBL8150041 | 0.78 | PPARG (0.72) | PPARGRXRA | |
| SCHEMBL8150043 | 0.78 | PPARG (0.72) | PPARGRXRA | |
| SCHEMBL7147839 | 0.78 | PPARG (0.72) | PPARGRXRA | |
| SCHEMBL8151007 | 0.73 | PPARG (0.60) | PPARGRXRA | |
| SCHEMBL8151005 | 0.73 | PPARG (0.60) | PPARGRXRA | |
| SCHEMBL8150999 | 0.73 | PPARG (0.60) | PPARGRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214876-B1 | PHOSPHOLIPASE INHIBITORS | ELI LILLY AND COMPANY | 2001-04-10 | — | — | US | disclosed |