Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28407153 | 0.76 | EPHX1 (0.35) | EPHX1 | |
| SCHEMBL425715 | 0.76 | EPHX1 (0.35) | EPHX1 | |
| SCHEMBL6426799 | 0.74 | EPHX1 (0.36) | EPHX1 | |
| SCHEMBL12418037 | 0.72 | EPHX1 (0.33) | EPHX1 | |
| SCHEMBL28216210 | 0.72 | DNM1 (0.32) | — | |
| SCHEMBL27751696 | 0.72 | DNM1 (0.32) | — | |
| SCHEMBL9586160 | 0.71 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL423499 | 0.70 | EPHX1 (0.41) | EPHX1 | |
| SCHEMBL5960735 | 0.70 | EPHX1 (0.41) | EPHX1 | |
| SCHEMBL424481 | 0.70 | EPHX1 (0.41) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269737-A | 2-hydroxycycloalkane-1-carbamoyl derivatives | 爱杜西亚药品有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-108601788-B | EIF 4A-inhibiting compounds and methods relating thereto | 效应治疗股份有限公司 | 2021-10-22 | — | — | CN | disclosed |
| US-6197963-B1 | TETRAHYDROPYRAN DERIVATIVES; PROTEIN G, SOMATOSTATIN, AND NATURAL KILLER CELL RECEPTOR ANTAGONISTS OR MIMETICS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2001-03-06 | — | — | US | disclosed |
| US-5811512-A | BINDING TO G-PROTEIN-LINKED RECEPTORS, SUBSTANCE P RECEPTOR; HORMONE INHIBITORS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-09-22 | — | — | US | disclosed |
| EP-0728007-A4 | NON-PEPTIDE PEPTIDOMIMETICS | UNIV PENNSYLVANIA (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997028172-A1 | NON-PEPTIDE PEPTIDOMIMETICS AND RELATED CYCLIC HEXAPEPTIDES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1997-08-07 | — | — | WO | disclosed |
| US-5552534-A | COMPOUNDS FOR CROSS REACTION WITH PEPTIDES FOR BINDING G PROTEIN | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1996-09-03 | — | — | US | disclosed |
| EP-0728007-A1 | NON-PEPTIDE PEPTIDOMIMETICS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995011686-A1 | NON-PEPTIDE PEPTIDOMIMETICS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1995-05-04 | — | — | WO | disclosed |