Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | MEN1 | O00255 | 9/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | S100B | P04271 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.39 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789351 | 0.87 | MAPT (0.47) | HPGDMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL20836396 | 0.87 | MAPT (0.40) | HPGDMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL806747 | 0.85 | MEN1 (0.42) | HPGDMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL24681526 | 0.84 | MAPT (0.40) | HPGDMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL24511350 | 0.83 | GAA (0.58) | MAPTKMT2AGAASMN1; SMN2KDM4E | |
| SCHEMBL44787 | 0.82 | MAPT (0.51) | HPGDMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL790815 | 0.82 | ALDH1A1 (0.48) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL18372265 | 0.81 | GAA (0.35) | MAPTALDH1A1GAAADRB1GFER | |
| SCHEMBL15753571 | 0.79 | ALDH1A1 (0.37) | HPGDMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30768491 | 0.79 | GAA (0.33) | MAPTGAAADRB1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |