Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.40 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | S100B | P04271 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30748846 | 0.88 | ALDH1A1 (0.47) | ALDH1A1LMNAHIF1AMAPTL3MBTL1 | |
| SCHEMBL17310043 | 0.88 | SIRT6 (0.49) | ALDH1A1MAPTHTTKMT2AGAA | |
| SCHEMBL791178 | 0.88 | ALDH1A1 (0.47) | ALDH1A1LMNAHIF1AMAPTL3MBTL1 | |
| SCHEMBL17394686 | 0.83 | SMN1; SMN2 (0.41) | LMNAMAPTL3MBTL1HTTKMT2A | |
| SCHEMBL30768488 | 0.82 | DPP4 (0.36) | ALDH1A1LMNAHIF1AMAPTKMT2A | |
| SCHEMBL806747 | 0.82 | MEN1 (0.42) | ALDH1A1LMNAMAPTL3MBTL1HTT | |
| SCHEMBL790345 | 0.82 | HPGD (0.44) | ALDH1A1LMNAMAPTL3MBTL1HTT | |
| SCHEMBL24681526 | 0.81 | MAPT (0.40) | ALDH1A1LMNAHIF1AMAPTL3MBTL1 | |
| SCHEMBL44787 | 0.79 | MAPT (0.51) | ALDH1A1LMNAMAPTL3MBTL1HTT | |
| SCHEMBL22040952 | 0.79 | MAPT (0.45) | ALDH1A1LMNAHIF1AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |