SCHEMBL7903473

SCHEMBL7903473

COC(=O)NC(=O)C(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)OC

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.67
PPARA Q07869 14/20 0.67
PPARD Q03181 4/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7903329 0.93 PPARG (0.70) PPARGPPARAPPARD
SCHEMBL7904769 0.92 PPARG (0.66) PPARGPPARAPPARD
SCHEMBL7904793 0.92 PPARG (0.75) PPARGPPARAPPARD
SCHEMBL7905678 0.91 PPARG (0.72) PPARGPPARAPPARD
SCHEMBL7904779 0.91 PPARG (0.77) PPARGPPARAPPARD
SCHEMBL7903537 0.89 PPARG (0.71) PPARGPPARAPPARD
SCHEMBL7903352 0.86 PPARG (0.72) PPARGPPARAPPARD
SCHEMBL7897370 0.86 PPARG (0.67) PPARGPPARAPPARD
SCHEMBL7897441 0.86 PPARG (0.81) PPARGPPARAPPARD
SCHEMBL7897332 0.85 PPARG (0.74) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204277-B1 TREATING DIABETES JAPAN TOBACCO INC. (JP) 2001-03-20 US claimed
EP-0930299-A1 PROPIONIC ACID DERIVATIVES AND APPLICATIONS THEREOF Japan Tobacco Inc. (JP) 1999-07-21 EP claimed
US-6204277-B1 TREATING DIABETES JAPAN TOBACCO INC. (JP) 2001-03-20 US disclosed
EP-0930299-A1 PROPIONIC ACID DERIVATIVES AND APPLICATIONS THEREOF Japan Tobacco Inc. (JP) 1999-07-21 EP disclosed