SCHEMBL7903501

SCHEMBL7903501

CCCCCC1CCC(c2ccc(OCc3ccc(OC(F)(F)C(F)C(F)(F)F)cc3)cc2)CC1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PLG P00747 4/20 0.36
PRSS1 P07477 4/20 0.36
PRSS2 P07478 4/20 0.36
PRSS3 P35030 4/20 0.36
SPHK1 Q9NYA1 3/20 0.36
SLC6A5 Q9Y345 1/20 0.35
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
HRH3 Q9Y5N1 2/20 0.34
MRGPRX4 Q96LA9 1/20 0.34
ITGB3 P05106 2/20 0.34
ITGA2B P08514 2/20 0.34
RAB9A P51151 1/20 0.34
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7914150 0.92 ALDH1A1 (0.40) SPHK1ALDH1A1TSHRHSD17B10HRH3
SCHEMBL7903604 0.91 SPHK1 (0.43) SPHK1ALDH1A1TSHRHSD17B10CYP2C9
SCHEMBL7917404 0.90 ALDH1A1 (0.39) SPHK1ALDH1A1TSHRHSD17B10CYP2C9
SCHEMBL7913769 0.90 ALDH1A1 (0.39) SPHK1ALDH1A1TSHRHSD17B10CYP2C9
SCHEMBL7903483 0.90 CYP2C9 (0.37) ALDH1A1TSHRHSD17B10HRH3MRGPRX4
SCHEMBL7917348 0.88 ALDH1A1 (0.38) SPHK1ALDH1A1TSHRHSD17B10RAB9A
SCHEMBL7911232 0.88 ALDH1A1 (0.38) SPHK1ALDH1A1TSHRHSD17B10HRH3
SCHEMBL7903622 0.88 ALDH1A1 (0.38) SPHK1ALDH1A1TSHRHSD17B10HRH3
SCHEMBL7917421 0.88 ALDH1A1 (0.41) SPHK1ALDH1A1TSHRHSD17B10HRH3
SCHEMBL7911190 0.88 ALDH1A1 (0.36) SPHK1ALDH1A1TSHRHSD17B10HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640578-B2 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 2001-06-27 EP disclosed
EP-0640578-B1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 1997-11-05 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed